Women's-health trial intelligence · Menopause
Menopause clinical trials: what changed
Menopause, perimenopause and hot flush (vasomotor symptom) trials that are recruiting, newly registered, recently updated or newly reporting results, drawn from both the US registry (ClinicalTrials.gov) and the EU registry (CTIS) on one page. Built for femtech business-development teams, women's-health investors, CROs and advocacy groups.
Also tracking: Endometriosis trials · PCOS trials
331trials on this page (open or active in last 90 days)
284open to recruitment now, or about to open
68registry records updated in last 30 days
136updated in last 90 days
60newly registered in last 90 days
0first results posted in last 90 days (US registry)
The last 90 days at a glance
Counts cover the 331 trials listed below. Site-location figures use the 245 open trials that list at least one site country.
By phase
By status
Most active lead sponsors
Industry-sponsored share (US registry rows): 15%
Where open trials have sites
US: 87 · EU-27: 68 · neither: 90 (of 245; a trial can count in both)
Ireland: menopause trials with an Irish site
1open menopause trial list an Irish site (2 on this page in total; 6 of 1,467 menopause records in both registries have ever listed Ireland). Use the Irish site filter on the table below to see them.
Want every trial with an Irish site, across all therapy areas? See the Ireland Trials Monitor preview.
Trial table
Newest registry update first. Every ID links to the official registry record. Download the data: CSV · JSON.
| ID | Title | Lead sponsor | Phase | Status | Start | Primary completion | Enrolment | Site countries | Sex eligible | Last update |
|---|---|---|---|---|---|---|---|---|---|---|
| NCT07272174 ClinicalTrials.gov |
Exercise in Perimenopause to Improve Cognitive Health Updated ≤30d | University of British Columbia | N/A (non-drug) | Recruiting | 2026-03-30 | 2026-12-15 (est.) | 50 | Canada | Female | 2026-10-20 |
| NCT07884357 ClinicalTrials.gov |
Nurse-Led Self-Compassion Intervention for Women With Induced Menopause NewUpdated ≤30d | Aya Ibrahim | N/A (non-drug) | Completed | 2026-01-15 | 2026-07-30 | 150 | Egypt | Female | 2026-10-20 |
| NCT07565675 ClinicalTrials.gov |
The BALANCE Study - Improving Glucose Control Through Prebiotic Gut Health Drink in Postmenopausal Women Updated ≤30d | University of Roehampton | N/A (non-drug) | Completed | 2026-06-10 | 2026-07-30 | 30 | United Kingdom | Female | 2026-10-20 |
| NCT07873177 ClinicalTrials.gov |
Internet-Delivered CBT Program for Menopausal Vasomotor Symptoms NewUpdated ≤30d | St. Joseph's Healthcare Hamilton | N/A (non-drug) | Not yet recruiting | 2026-10-13 (est.) | 2028-05-31 (est.) | 50 | Canada | Female | 2026-10-20 |
| NCT07880041 ClinicalTrials.gov |
Evaluation of the Effect of a Nutraceutical Supplement on Hair Growth and Hair Quality in Premenopausal and Menopausal Women NewUpdated ≤30d | LycoRed Ltd. | N/A (non-drug) | Recruiting | 2026-06-01 | 2027-01 (est.) | 60 | France | Female | 2026-10-19 |
| NCT07874399 ClinicalTrials.gov |
Time-Restricted Eating and Personalized Energy-Restricted Diet in Obese Postmenopausal Women NewUpdated ≤30d | Gazi University | N/A (non-drug) | Not yet recruiting | 2026-11-01 (est.) | 2027-10-24 (est.) | 40 | Turkey (Türkiye) | Female | 2026-10-19 |
| NCT07386249 ClinicalTrials.gov |
Exploration of the Effect of a Wheat Polar Lipid Complex on Vaginal Dryness in Healthy Postmenopausal Women Updated ≤30d | Seppic | N/A (non-drug) | Recruiting | 2026-02-02 | 2027-03 (est.) | 110 | Belgium | Female | 2026-10-19 |
| NCT07865377 ClinicalTrials.gov |
Serum Endogenous Estrogens, Estrogen Receptors, and Sirtuin-1 and -3 After Resveratrol Supplementation NewUpdated ≤30d | InCor Heart Institute | N/A (non-drug) | Recruiting | 2026-08-24 | 2029-08-24 (est.) | 80 | Brazil | Female | 2026-10-16 |
| NCT07871396 ClinicalTrials.gov |
Exercise Training Intensity and Nitrate Supplementation in Post-Menopausal Females on Hormone Therapy NewUpdated ≤30d | University of Virginia | N/A (non-drug) | Not yet recruiting | 2026-10-15 (est.) | 2027-11-30 (est.) | 24 | United States | Female | 2026-10-16 |
| NCT07860645 ClinicalTrials.gov |
Effect of Lifestyle Intervention on Menopausal Symptoms, Sleep Quality, and Anxiety in Peri- and Postmenopausal Women NewUpdated ≤30d | Konya Beyhekim Training and Research Hospital | N/A (non-drug) | Recruiting | 2026-10-15 | 2027-05-15 (est.) | 100 | Turkey (Türkiye) | Female | 2026-10-16 |
| NCT07878741 ClinicalTrials.gov |
The Effects of Menopausal Status, Isoflavone Supplementation and Training on Cardiometabolic Function Women NewUpdated ≤30d | University of Copenhagen | N/A (non-drug) | Not yet recruiting | 2027-10-15 (est.) | 2029-06-01 (est.) | 60 | Denmark | Female | 2026-10-16 |
| NCT00001231 ClinicalTrials.gov |
Perimenopause-Related Mood and Behavioral Disorders Updated ≤30d | National Institute of Mental Health (NIMH) | Observational | Completed | 1989-03-06 | — | 1,158 | United States | Female | 2026-10-16 |
| NCT06715514 ClinicalTrials.gov |
Menopausal Hormone Therapy, GLP-1 Agonists, and Glucose and Energy Homeostasis in Postmenopausal Women With Overweight/Obesity and Impaired Glucose Homeostasis Updated ≤30d | Lia Bally | N/A (non-drug) | Active, not recruiting | 2025-02-18 | 2026-12-17 (est.) | 96 | Switzerland | Female | 2026-10-16 |
| NCT05903820 ClinicalTrials.gov |
Rhythmic Estradiol and Bone Health Updated ≤30d | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | Phase 4 | Completed | 2023-07-19 | 2024-10-21 | 48 | Netherlands | Female | 2026-10-16 |
| NCT07619352 ClinicalTrials.gov |
Evaluation of the Effects of Lifestyle Medicine and Mindfulness-based Group Medical Visits on Stress, Microbiome, and Quality of Life in Women Experiencing Perimenopause and Menopause Updated ≤30d | Ohio State University | N/A (non-drug) | Not yet recruiting | 2027-01-01 (est.) | 2028-01-01 (est.) | 40 | United States | Female | 2026-10-16 |
| NCT07874893 ClinicalTrials.gov |
Self-Management Box on Hot Flash in Postmenopausal Women NewUpdated ≤30d | Mansoura University | N/A (non-drug) | Not yet recruiting | 2026-10-08 (est.) | 2027-05-01 (est.) | 120 | Egypt | Female | 2026-10-15 |
| NCT07667699 ClinicalTrials.gov |
Multidimensional Determinants of Functional Health In Women Aged 45-60 Updated ≤30d | Kartal City Hospital | Observational | Enrolling by invitation | 2026-07-01 | 2026-12-31 (est.) | 200 | Turkey (Türkiye) | Female | 2026-10-14 |
| NCT07850050 ClinicalTrials.gov |
SYNCHRONIZE®-HERA: A Study to Test Whether Survodutide Helps Women Who Are Living With Overweight or Obesity and Are Going Through or Have Finished Menopause, to Lose Weight NewUpdated ≤30d | Boehringer Ingelheim | Phase 3 | Not yet recruiting | 2026-10-31 (est.) | 2028-07-26 (est.) | 600 | United States | Female | 2026-10-14 |
| NCT07757724 ClinicalTrials.gov |
Chinese Herbal Sachet Therapy for Sleep Quality in Menopausal Women NewUpdated ≤30d | Macao Polytechnic University | N/A (non-drug) | Completed | 2023-12-01 | 2024-03-31 | 122 | Macau | Female | 2026-10-14 |
| NCT04837729 ClinicalTrials.gov |
The Effect of Acupressure Applied to Menopausal Women on Menopausal Symptoms and Quality of Life Updated ≤30d | Mersin University | N/A (non-drug) | Completed | 2021-05-15 | 2021-06-15 | 61 | Turkey (Türkiye) | Female | 2026-10-13 |
| NCT05859594 ClinicalTrials.gov |
The Effect of Laughter Yoga on Vasomotor Symptoms and Sleep Quality Updated ≤30d | Mersin University | N/A (non-drug) | Completed | 2023-05-02 | 2023-07-31 | 36 | Turkey (Türkiye) | Female | 2026-10-13 |
| NCT07863973 ClinicalTrials.gov |
Effects of a Dietary Supplement in Women With Late Perimenopause or Early Postmenopause NewUpdated ≤30d | University of Alicante | N/A (non-drug) | Recruiting | 2026-11-01 (est.) | 2027-02-28 (est.) | 120 | Spain | Female | 2026-10-13 |
| NCT07042516 ClinicalTrials.gov |
Safety and Efficacy of Asimadoline (TP0052) in Patients With Vasomotor Symptoms (VMS). Updated ≤30d | Tioga Pharmaceuticals | Phase 2 | Recruiting | 2025-08-13 | 2027-10-31 (est.) | 120 | United States | Female | 2026-10-08 |
| NCT07863739 ClinicalTrials.gov |
CO₂ Laser With or Without Platelet-Rich Plasma for Genitourinary Syndrome of Menopause NewUpdated ≤30d | National and Kapodistrian University of Athens | N/A (non-drug) | Completed | 2023-06-01 | 2025-04-01 | 40 | Greece | Female | 2026-10-08 |
| NCT07859761 ClinicalTrials.gov |
Womens Health Screening and the Oral Microbiome NewUpdated ≤30d | University of Plymouth | Observational | Not yet recruiting | 2026-10-01 (est.) | 2029-07-01 (est.) | 240 | United Kingdom | Female | 2026-10-06 |
| NCT07861295 ClinicalTrials.gov |
Satavari and Ashoka for Menopause (SAM) Study NewUpdated ≤30d | Vidya USA Corporation | N/A (non-drug) | Recruiting | 2025-10-01 | 2026-12-01 (est.) | 50 | United States | Female | 2026-10-06 |
| NCT07860424 ClinicalTrials.gov |
Women in Action: A Multicomponent Intervention for Older Women NewUpdated ≤30d | Universidad de Oviedo | N/A (non-drug) | Not yet recruiting | 2026-11 (est.) | 2027-12 (est.) | 214 | Spain | Female | 2026-10-06 |
| NCT07105163 ClinicalTrials.gov |
Evaluation of Adherence With Bisphosphonates and Calcium and Vitamin D Supplements in Women With Postmenopausal Osteoporosis Updated ≤30d | Procare Health Iberia S.L. | Observational | Completed | 2025-03-03 | 2025-12-03 | 230 | Spain | Female | 2026-10-06 |
| NCT07218445 ClinicalTrials.gov |
The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity Updated ≤30d | Mayo Clinic | Phase 4 | Recruiting | 2026-04-08 | 2027-09-18 (est.) | 40 | United States | Female | 2026-10-06 |
| NCT05570721 ClinicalTrials.gov |
Depression, Aging, Stress and Heart Health Study Updated ≤30d | University of North Carolina, Chapel Hill | N/A (non-drug) | Completed | 2022-11-16 | 2025-02-25 | 41 | United States | Female | 2026-10-05 |
| NCT07361757 ClinicalTrials.gov |
Qualia Perimenopause Efficacy and Tolerability Study: An Open-label 3-Arm Trial Updated ≤30d | Qualia Life Sciences | N/A (non-drug) | Completed | 2026-03-16 | 2026-04-22 | 66 | United States | Female | 2026-10-05 |
| NCT07858994 ClinicalTrials.gov |
Effects of Fractional CO2 Vaginal Laser in Postmenopausal Women With Genitourinary Syndrome of Menopause NewUpdated ≤30d | Karina Amar Svec | N/A (non-drug) | Completed | 2023-11-09 | 2025-07-31 | 10 | Brazil | Female | 2026-10-05 |
| NCT05440617 ClinicalTrials.gov |
Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy Updated ≤30d | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Observational | Recruiting | 2022-07-22 | 2041-09-21 (est.) | 100 | United States | Female | 2026-10-02 |
| NCT06552091 ClinicalTrials.gov |
Guided Digital Self-Hypnosis Solution for Managing Hot Flashes in Patients Undergoing Adjuvant Hormone Therapy Updated ≤30d | Institut de Cancérologie de Lorraine | N/A (non-drug) | Recruiting | 2024-12-20 | 2027-09-20 (est.) | 76 | France | Female | 2026-10-02 |
| NCT05571514 ClinicalTrials.gov |
Study of the Impact of Mother-of-pearl Nutritional Supplementation on the Prevention of Post-menopausal Osteoporosis Updated ≤30d | Centre Hospitalier Universitaire de Saint Etienne | N/A (non-drug) | Recruiting | 2023-05-12 | 2027-11 (est.) | 200 | France | Female | 2026-10-02 |
| NCT07663305 ClinicalTrials.gov |
Evaluation of a Mobile Menopause Application Updated ≤30d | Endo Health GmbH | N/A (non-drug) | Recruiting | 2026-07-06 | 2027-05 (est.) | 426 | Germany | Female | 2026-10-02 |
| NCT06798571 ClinicalTrials.gov |
Role of Menopause in Thermoregulation Updated ≤30d | Penn State University | Phase 4 | Recruiting | 2025-03-01 | 2026-12-01 (est.) | 24 | United States | Female | 2026-10-02 |
| NCT07672002 ClinicalTrials.gov |
Cuidar-ME, a Web-based Psychological Intervention for (Peri)Menopausal Women: A Pilot Randomized Controlled Trial Updated ≤30d | University of Coimbra | N/A (non-drug) | Active, not recruiting | 2026-09-01 | 2027-02-01 (est.) | 150 | Portugal | Female | 2026-10-01 |
| NCT07005648 ClinicalTrials.gov |
Brazilian Registry of Menopausal Health Updated ≤30d | Science Valley Research Institute | Observational | Recruiting | 2026-09-11 | 2027-09-11 (est.) | 1,592 | Brazil | All | 2026-10-01 |
| NCT07851662 ClinicalTrials.gov |
Functional Mobility and Resistance Exercise for Postmenopausal Females With Type 1 Diabetes NewUpdated ≤30d | Institut de Recherches Cliniques de Montreal | N/A (non-drug) | Not yet recruiting | 2026-12 (est.) | 2030-09 (est.) | 63 | Canada | Female | 2026-10-01 |
| 2026-525569-30-00 EU CTIS |
A study to learn how a high-fat meal affects the way elinzanetant is taken up by the body in healthy women Updated ≤30d | Bayer AG | Phase 1 | Ongoing, recruitment ended | 2026-09-08 | — | — | Germany | Female | 2026-10-01 |
| NCT07848438 ClinicalTrials.gov |
Sex Hormones and Aging NewUpdated ≤30d | University of Michigan | N/A (non-drug) | Recruiting | 2026-08-20 | 2031-08 (est.) | 120 | United States | Female | 2026-09-30 |
| NCT07850167 ClinicalTrials.gov |
Menstrual Cycle, Menopause, and Pain Perception During Endodontic Treatment NewUpdated ≤30d | Nigde Omer Halisdemir University | Observational | Recruiting | 2026-03-10 | 2027-03 (est.) | 130 | Turkey (Türkiye) | Female | 2026-09-30 |
| NCT07408440 ClinicalTrials.gov |
Transdermal Testosterone Gel for Female Sexual Interest and Arousal Disorder in Peri- and Post Menopause Updated ≤30d | The University of Texas Health Science Center, Houston | N/A (non-drug) | Not yet recruiting | 2027-01-01 (est.) | 2028-03-30 (est.) | 150 | United States | Female | 2026-09-29 |
| NCT07688720 ClinicalTrials.gov |
Transcutaneous Auricular Neurostimulation (tAN) for Premenstrual Dysphoric Disorder (PMDD) and Perimenopause Updated ≤30d | Texas Christian University | N/A (non-drug) | Recruiting | 2026-10 (est.) | 2027-03 (est.) | 20 | United States | Female | 2026-09-29 |
| NCT07822230 ClinicalTrials.gov |
Effects of a Dietary Intervention Based on the Dietary Guidelines for the Brazilian Population on the Reduction of Menopausal Symptoms in Overweight and Obese Women NewUpdated ≤30d | Federal University of Health Science of Porto Alegre | N/A (non-drug) | Recruiting | 2026-05-06 | 2027-07-30 (est.) | 74 | Brazil | Female | 2026-09-29 |
| NCT07829653 ClinicalTrials.gov |
A Study to Confirm if Fezolinetant Helps to Reduce Hot Flashes in Indian Women Going Through Menopause NewUpdated ≤30d | Astellas Pharma Inc | Phase 3 | Not yet recruiting | 2026-10-31 (est.) | 2028-03-31 (est.) | 100 | — | Female | 2026-09-28 |
| NCT06673199 ClinicalTrials.gov |
The Influence of the "Washoku" Diet on the Gut Microbiota in Postmenopausal Women Updated ≤30d | Joanna Bajerska | N/A (non-drug) | Completed | 2024-11-16 | 2025-05-31 | 35 | Poland | Female | 2026-09-28 |
| NCT07842614 ClinicalTrials.gov |
Effect of a Brassicaceae-Enriched Diet on Menopausal Symptoms in Women With Breast Cancer Receiving Antiestrogen Therapy NewUpdated ≤30d | Azienda Ospedaliero, Universitaria Pisana | N/A (non-drug) | Completed | 2020-10-30 | 2024-10-01 | 81 | Italy | Female | 2026-09-25 |
| NCT07633743 ClinicalTrials.gov |
MenoZen VR for Menopause Symptom Management Updated ≤30d | Mayo Clinic | N/A (non-drug) | Recruiting | 2026-09-28 (est.) | 2027-07-31 (est.) | 40 | United States | Female | 2026-09-24 |
| NCT07839299 ClinicalTrials.gov |
Bonafide Sleep Supplement for Menopausal Women With Impaired Sleep NewUpdated ≤30d | Bonafide Health | N/A (non-drug) | Completed | 2025-01-03 | 2025-08-23 | 90 | United States | Female | 2026-09-24 |
| NCT07839312 ClinicalTrials.gov |
Bonafide Sleep Supplement for Menopausal Women With Sleep Complaints NewUpdated ≤30d | Bonafide Health | N/A (non-drug) | Completed | 2025-01-03 | 2025-07-01 | 111 | United States | Female | 2026-09-24 |
| NCT07490431 ClinicalTrials.gov |
An Observational Study to Learn More About How Elinzanetant is Used and How Well it Works for Women With Menopause Symptoms in United States Updated ≤30d | Bayer | Observational | Not yet recruiting | 2026-11-30 (est.) | 2029-11-30 (est.) | 2,400 | — | Female | 2026-09-24 |
| NCT07839416 ClinicalTrials.gov |
On the Effect of a Hybrid Health Literacy Intervention on Sexual Function and Digital Health Literacy in Menopausal Women NewUpdated ≤30d | Kahramanmaras Sutcu Imam University | N/A (non-drug) | Not yet recruiting | 2026-10-01 (est.) | 2026-11-05 (est.) | 128 | Turkey (Türkiye) | Female | 2026-09-24 |
| NCT07216742 ClinicalTrials.gov |
Human Menopausal Gonadotropin Research in Infertility Assessing Cumulative Live Birth With Frozen Embryo Transfer. Updated ≤30d | Granata Bio Corporation | Phase 3 | Recruiting | 2025-11-01 | 2028-11 (est.) | 659 | United States | Female | 2026-09-24 |
| NCT06774885 ClinicalTrials.gov |
Role of Folic Acid in the Management of Adjuvant Endocrine Therapy-Induced Hot Flashes in Breast Cancer Patients Updated ≤30d | Future University in Egypt | Phase 3 | Completed | 2025-04-05 | 2025-10-22 | 120 | Egypt | Female | 2026-09-23 |
| NCT07834944 ClinicalTrials.gov |
ROSA-B: ALAN Exposure and Brain Health in Midlife Women With VMS NewUpdated ≤30d | Beth Israel Deaconess Medical Center | N/A (non-drug) | Not yet recruiting | 2026-11-01 (est.) | 2030-11-01 (est.) | 66 | — | Female | 2026-09-22 |
| NCT06440967 ClinicalTrials.gov |
A Study to Confirm if Fezolinetant Helps Reduce Hot Flashes in Women With Breast Cancer Who Are Having Hormone Therapy Updated ≤30d | Astellas Pharma Global Development, Inc. | Phase 3 | Active, not recruiting | 2024-07-31 | 2026-06-25 | 982 | Canada, Czechia, Denmark +8 | Female | 2026-09-22 |
| NCT07351006 ClinicalTrials.gov |
Exercise as Medicine: A Non-Pharmacological Approach to Menopausal Symptoms Updated ≤30d | Linnaeus University | N/A (non-drug) | Recruiting | 2025-11-01 | 2027-05 (est.) | 45 | Sweden | Female | 2026-09-22 |
| NCT07834216 ClinicalTrials.gov |
The Effect of Structured Health Information-Seeking Training on Cyberchondria and E-Health Literacy in Menopausal Women: A Randomized Controlled Trial NewUpdated ≤30d | Istanbul University | N/A (non-drug) | Not yet recruiting | 2027-01-24 (est.) | 2027-03-30 (est.) | 60 | — | Female | 2026-09-22 |
| NCT07834463 ClinicalTrials.gov |
Randomized Evaluation of Natural Extract for Menopausal Wellness (RENEW) NewUpdated ≤30d | India Glycols Ltd | N/A (non-drug) | Recruiting | 2026-09-01 | 2027-08-31 (est.) | 100 | United States | Female | 2026-09-22 |
| NCT06976112 ClinicalTrials.gov |
Impact of Lean Pork on Endothelial Function in Perimenopause Updated ≤30d | Pennington Biomedical Research Center | N/A (non-drug) | Recruiting | 2025-08-01 | 2026-12-31 (est.) | 30 | United States | Female | 2026-09-22 |
| 2024-510719-31-00 EU CTIS |
A Randomized, Placebo-controlled, Double-blind, Phase 3 Clinical Study to Investigate the Efficacy and Safety of Fezolinetant for Treatment of Moderate to Severe Vasomotor Symptoms (Hot Flashes) in Women with Stage 0 to 3 Hormone Receptor-positive Breast Cancer Who Are Receiving Adjuvant Endocrine Therapy Updated ≤30d | Astellas Pharma Global Development Inc. | Phase 3 | Ongoing, recruitment ended | 2025-01-24 | — | — | Czechia, Denmark, France +6 | Female | 2026-09-22 |
| NCT07824947 ClinicalTrials.gov |
Effects of Strength Training on the Gait and Pelvic Floor in Menopausal Women NewUpdated ≤30d | University of Alcala | N/A (non-drug) | Completed | 2023-04-01 | 2023-07-31 | 34 | Spain | Female | 2026-09-21 |
| NCT07653620 ClinicalTrials.gov |
Hydration & Female Life Stages Updated ≤30d | PepsiCo Global R&D | N/A (non-drug) | Recruiting | 2026-06-29 | 2026-11 (est.) | 72 | United States | Female | 2026-09-21 |
| NCT06425978 ClinicalTrials.gov |
Efficacy of the Use of Cellular Matrix/ A-CP-HA Kit Updated ≤30d | Fundación Santiago Dexeus Font | Phase 4 | Completed | 2024-05-30 | 2026-03-23 | 192 | Spain | Female | 2026-09-21 |
| NCT07831499 ClinicalTrials.gov |
Cyclic vs. Constant Estradiol: Regimens' Effects on Brain Health NewUpdated ≤30d | University of Colorado, Denver | Phase 4 | Recruiting | 2026-07-15 | 2028-07-15 (est.) | 40 | United States | Female | 2026-09-21 |
| NCT07574216 ClinicalTrials.gov |
VEDA Study (DHEA vs Estradiol) Updated ≤30d | University of Arizona | N/A (non-drug) | Recruiting | 2026-08-04 | 2031-12-31 (est.) | 324 | United States | Female | 2026-09-21 |
| NCT07824648 ClinicalTrials.gov |
Thermoregulatory Physiology of Menopausal Hot Flashes NewUpdated ≤90d | SRI International | N/A (non-drug) | Recruiting | 2026-05-05 | 2027-09-15 (est.) | 40 | United States | Female | 2026-09-17 |
| NCT07800793 ClinicalTrials.gov |
Effects of a Mobile Game in Menopausal Women NewUpdated ≤90d | Medipol University | N/A (non-drug) | Not yet recruiting | 2026-10-15 (est.) | 2027-09-15 (est.) | 82 | Turkey (Türkiye) | Female | 2026-09-17 |
| NCT07260604 ClinicalTrials.gov |
HIFEM for Incontinence After Menopause High-Intensity Focused Electromagnetic (HIFEM) Updated ≤90d | Göteborg University | N/A (non-drug) | Not yet recruiting | 2026-10-15 (est.) | 2027-12-31 (est.) | 100 | Sweden | Female | 2026-09-15 |
| NCT07132385 ClinicalTrials.gov |
Feasibility of Different Types of Exercise Training in Perimenopausal Females Updated ≤90d | University of Toronto | N/A (non-drug) | Recruiting | 2025-09-01 | 2026-12-30 (est.) | 30 | Canada | Female | 2026-09-15 |
| NCT07751029 ClinicalTrials.gov |
Haelan 951 for Menopause Symptoms in Peri- and Postmenopausal Women NewUpdated ≤90d | Spectrum Clinical Research, LLC | N/A (non-drug) | Recruiting | 2026-09-21 (est.) | 2026-10 (est.) | 25 | United States | Female | 2026-09-11 |
| NCT06580470 ClinicalTrials.gov |
Improving Functioning Among Aging Women Veterans Updated ≤90d | VA Office of Research and Development | N/A (non-drug) | Not yet recruiting | 2026-12-01 (est.) | 2027-12-01 (est.) | 48 | United States | Female | 2026-09-10 |
| NCT07794150 ClinicalTrials.gov |
A Study to Assess the Skin Irritation and Sensitization of Estradiol/Levonorgestrel TDS in Healthy Postmenopausal Subjects NewUpdated ≤90d | Corium Innovations, Inc. | Phase 1 | Recruiting | 2026-08-10 | 2027-05-31 (est.) | 250 | India, United States | Female | 2026-09-10 |
| NCT07674680 ClinicalTrials.gov |
Beta3-adrenergic Receptors and Cardiovascular Function in Aging Women Updated ≤90d | University of Missouri-Columbia | Early Phase 1 | Recruiting | 2026-07-31 | 2028-05 (est.) | 60 | United States | Female | 2026-09-10 |
| NCT07814300 ClinicalTrials.gov |
DBPCT Effects of Omega-3 FA on Memory and Cognition in Peri- and Menopausal Women NewUpdated ≤90d | St. Mary's University, Twickenham | N/A (non-drug) | Active, not recruiting | 2026-03-25 | 2026-08-30 | 42 | United Kingdom | Female | 2026-09-10 |
| NCT06417177 ClinicalTrials.gov |
Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia Updated ≤90d | University of Missouri-Columbia | Early Phase 1 | Recruiting | 2024-06-03 | 2026-12 (est.) | 75 | United States | Female | 2026-09-10 |
| NCT07810959 ClinicalTrials.gov |
Breast and Vascular Effects of Menopausal Hormone Therapy in Postmenopausal Women NewUpdated ≤90d | Sanliurfa Mehmet Akif Inan Education and Research Hospital | Observational | Recruiting | 2026-06-01 | 2027-05-31 (est.) | 120 | Turkey (Türkiye) | Female | 2026-09-09 |
| NCT05846698 ClinicalTrials.gov |
The Effects of Luo-Bu-Fu-Ke-Bi-RI Pill Updated ≤90d | Guoqing Zhou | Observational | Completed | 2021-09-05 | 2025-06-25 | 300 | China | Female | 2026-09-09 |
| NCT07333885 ClinicalTrials.gov |
Impact of Reducose® on Glycemic Response and Menopausal Symptoms in Perimenopausal Women (CALM-R) Updated ≤90d | Phynova Group Ltd | N/A (non-drug) | Completed | 2025-12-12 | 2026-08-01 | 84 | United States | Female | 2026-09-09 |
| NCT06866119 ClinicalTrials.gov |
Effects of Estrogen on Heart Health in Women With Primary Ovarian Insufficiency Updated ≤90d | Massachusetts General Hospital | Observational | Recruiting | 2026-06-22 | 2028-06-30 (est.) | 45 | United States | Female | 2026-09-08 |
| 2025-522558-37-00 EU CTIS |
COMPASS - COpenhagen MenoPAuSe Study Updated ≤90d | Region Hovedstaden | Phase 2 | Authorised, recruitment pending | — | — | — | Denmark | Female | 2026-09-07 |
| NCT07310485 ClinicalTrials.gov |
Examining the Impact of Phytoestrogens Supplementation on the Gene Expression, and Premenstrual Syndrome in Primenopausal Women Updated ≤90d | University of Jordan | N/A (non-drug) | Enrolling by invitation | 2025-11-01 | 2026-05-25 | 50 | Jordan | Female | 2026-09-04 |
| NCT07611305 ClinicalTrials.gov |
ProGo Menopause Wellbeing Study Updated ≤90d | Hofseth Biocare ASA | N/A (non-drug) | Not yet recruiting | 2026-10 (est.) | 2026-12 (est.) | 100 | United States | Female | 2026-09-03 |
| NCT07797296 ClinicalTrials.gov |
Predictors of Religious Orientation Attitudes in Menopausal Women NewUpdated ≤90d | KTO Karatay University | Observational | Recruiting | 2026-08-26 | 2027-02-01 (est.) | 97 | Turkey (Türkiye) | Female | 2026-09-01 |
| NCT07472205 ClinicalTrials.gov |
Foot and Ankle Strengthening Program to Improve Physical Function in Menopausal Women (FAMEX) Updated ≤90d | University of Malaga | N/A (non-drug) | Not yet recruiting | 2026-09-01 (est.) | 2027-01-15 (est.) | 70 | Spain | Female | 2026-08-31 |
| NCT07713095 ClinicalTrials.gov |
Waning Moon: A Whole Person Health Intervention Designed by and for Urban Menopausal American Indian/Alaska Native Women Updated ≤90d | University of Utah | N/A (non-drug) | Not yet recruiting | 2026-08-01 (est.) | 2027-06-30 (est.) | 30 | — | Female | 2026-08-27 |
| NCT07242391 ClinicalTrials.gov |
Menopausal Hormone Therapy And Left Ventricular Function Updated ≤90d | Mayo Clinic | Observational | Recruiting | 2026-08-26 | 2027-12 (est.) | 50 | United States | Female | 2026-08-27 |
| NCT06238700 ClinicalTrials.gov |
Study on Allopregnanolone and Depression in Women Across the Menopause Transition Updated ≤90d | Beth Israel Deaconess Medical Center | N/A (non-drug) | Recruiting | 2026-05-01 | 2027-12-01 (est.) | 80 | United States | Female | 2026-08-26 |
| NCT07044284 ClinicalTrials.gov |
The Effects of Fractal Mindfulness Virtual Reality on Menopause Symptoms Updated ≤90d | London Metropolitan University | N/A (non-drug) | Completed | 2025-02-02 | 2025-05-30 | 18 | United Kingdom | Female | 2026-08-25 |
| NCT07784400 ClinicalTrials.gov |
Inflammation, Autoimmunity and Healthy Ageing in Menopause Transition. An Observational, Cross-sectional Study NewUpdated ≤90d | Fondazione IRCCS Policlinico San Matteo di Pavia | Observational | Not yet recruiting | 2026-09 (est.) | 2028-09 (est.) | 300 | Italy | Female | 2026-08-25 |
| NCT07782853 ClinicalTrials.gov |
A Randomized, Double-blind, Placebo-controlled, Parallel Study to Assess the Effect of Sinetrol on Body Composition &Metabolic Health in Peri-menopausal/Early Menopausal Women NewUpdated ≤90d | DR Healthcare - biotexia | N/A (non-drug) | Not yet recruiting | 2026-09 (est.) | 2028-08 (est.) | 200 | — | Female | 2026-08-24 |
| NCT07548307 ClinicalTrials.gov |
Radicle Revive™: A Study Assessing the Impact of Health and Wellness Products on Menopausal-Related Health Issues Associated Health Outcomes and Related Health Outcomes Updated ≤90d | Radicle Science | N/A (non-drug) | Active, not recruiting | 2026-04-09 | 2027-04-07 (est.) | 990 | United States | Female | 2026-08-20 |
| 2026-526442-28-00 EU CTIS |
Effects of Menopausal Hormone Therapy on QTc in Genetically Confirmed Long QT Syndrome: A Prospective Randomized Sequential Crossover Study with Long-Term Observational Follow-Up (LQTS-HER) NewUpdated ≤90d | Oslo Universitetssykehus HF | Phase 4 | Authorised, recruitment pending | — | — | — | Norway | Female | 2026-08-20 |
| NCT07771946 ClinicalTrials.gov |
Audio-Described Menopause Education Program in Visually Impaired Women NewUpdated ≤90d | Ankara University | N/A (non-drug) | Completed | 2025-02-15 | 2025-07-15 | 46 | Turkey (Türkiye) | Female | 2026-08-19 |
| NCT07606664 ClinicalTrials.gov |
Fezolinetant and Vascular Health and Brain Health Updated ≤90d | Rebecca Thurston | Phase 3 | Not yet recruiting | 2026-09-25 (est.) | 2029-11-30 (est.) | 220 | United States | Female | 2026-08-19 |
| NCT07594002 ClinicalTrials.gov |
Comparing Acupuncture vs. Sham Acupuncture for the Management of Hot Flashes in Prostate Cancer Patients Receiving Hormone Therapy Updated ≤90d | University of Kentucky | N/A (non-drug) | Recruiting | 2026-08-13 | 2028-08-31 (est.) | 40 | United States | All | 2026-08-18 |
| NCT07660315 ClinicalTrials.gov |
Goji Berry and Vasomotor Symptoms Pilot Study Updated ≤90d | University of California, Davis | N/A (non-drug) | Not yet recruiting | 2026-10-25 (est.) | 2027-06-30 (est.) | 6 | United States | Female | 2026-08-18 |
| NCT07767318 ClinicalTrials.gov |
Therapeutic Touch and Foot Reflexology on Sleep Quality and Menopausal Symptoms NewUpdated ≤90d | Osmaniye Korkut Ata University | N/A (non-drug) | Completed | 2025-08-15 | 2026-01-15 | 155 | Turkey (Türkiye) | Female | 2026-08-17 |
| NCT03681678 ClinicalTrials.gov |
Laser Therapy for Treatment of Urogenital Symptoms in Women Updated ≤90d | Corewell Health East | Observational | Completed | 2018-10-08 | 2022-12-15 | 100 | United States | Female | 2026-08-17 |
| NCT06925139 ClinicalTrials.gov |
Efficacy of Non-Ablative Radiofrequency on Vaginal and Sexual Health in Postmenopausal Women Updated ≤90d | University of Castilla-La Mancha | N/A (non-drug) | Completed | 2024-06-15 | 2024-12-30 | 62 | Spain | Female | 2026-08-17 |
| NCT07533097 ClinicalTrials.gov |
The Effect of Cold Packs on Hot Flushes and Depression in Women Going Through the Climacteric Period Updated ≤90d | Rabia Atilla | N/A (non-drug) | Completed | 2026-04-13 | 2026-08-01 | 60 | Turkey (Türkiye) | Female | 2026-08-13 |
| NCT06826755 ClinicalTrials.gov |
Melatonin Effects on Cardiovascular Disease Mechanisms in Midlife Women: A Randomized Clinical Trial Updated ≤90d | Mayo Clinic | N/A (non-drug) | Recruiting | 2025-05-23 | 2027-09 (est.) | 70 | United States | Female | 2026-08-13 |
| NCT07763509 ClinicalTrials.gov |
Calcium-Rich Food Versus Calcium Carbonate for Bone Health NewUpdated ≤90d | Cornell University | N/A (non-drug) | Not yet recruiting | 2026-09-01 (est.) | 2027-06-01 (est.) | 217 | United States | Female | 2026-08-13 |
| NCT07762287 ClinicalTrials.gov |
Evaluation of Possible Ways the Body May Process Two Different Forms of Elinzanetant in Healthy Study Participants NewUpdated ≤90d | Bayer | Phase 1 | Recruiting | 2026-07-22 | 2027-02-22 (est.) | 100 | Canada | Female | 2026-08-13 |
| NCT07759830 ClinicalTrials.gov |
A Feasibility Study of a Group Talking Therapy Programme for NHS Staff With Menopausal Hot Flushes and Night Sweats. NewUpdated ≤90d | Queen's University, Belfast | N/A (non-drug) | Completed | 2025-05-08 | 2026-01-30 | 35 | United Kingdom | Female | 2026-08-12 |
| NCT07759908 ClinicalTrials.gov |
Effects of a Synbiotic Intervention on Perimenopausal/Menopausal Symptoms NewUpdated ≤90dIreland | University College Cork | N/A (non-drug) | Completed | 2025-06-06 | 2025-09-30 | 49 | Ireland | Female | 2026-08-12 |
| NCT07572578 ClinicalTrials.gov |
Radicle Women's HealthTM: A Study Assessing the Impact of Health and Wellness Products on Fatigue and Related Health Outcomes Among Women Experiencing Menopausal Symptoms Updated ≤90d | Radicle Science | N/A (non-drug) | Completed | 2026-05-07 | 2026-08-05 | 502 | United States | Female | 2026-08-12 |
| NCT07724522 ClinicalTrials.gov |
Prebiotic Inulin for Late-Reproductive Individuals NewUpdated ≤90d | George Washington University | N/A (non-drug) | Recruiting | 2026-08-01 | 2028-02 (est.) | 27 | United States | Female | 2026-08-11 |
| NCT07752641 ClinicalTrials.gov |
Effect of HIFAS MENOPAUSE on Quality of Life in Postmenopausal Women NewUpdated ≤90d | Hifas da Terra S.L. | N/A (non-drug) | Completed | 2025-02-14 | 2026-01-14 | 20 | Spain | Female | 2026-08-11 |
| NCT07455812 ClinicalTrials.gov |
A Study in Germany to Learn About the Value of Fezolinetant in Treating Hot Flashes and Night Sweats in Women During Menopause Updated ≤90d | Astellas Pharma Europe Ltd. | Observational | Completed | 2024-10-29 | 2026-07-16 | 105 | Germany | Female | 2026-08-10 |
| NCT07754630 ClinicalTrials.gov |
Analysis of the Hormonal Implant and Transdermal Estradiol Gel in Climacteric Women NewUpdated ≤90d | Nutrindo Ideais Research Center | Phase 2 | Active, not recruiting | 2025-02-25 | 2026-05-01 | 50 | Brazil | Female | 2026-08-10 |
| NCT07750080 ClinicalTrials.gov |
The Effect of Multimodal Approach of Electrotherapy Versus Shock Wave Therapy in Menopausal Women With Tennis Elbow. NewUpdated ≤90d | October 6 University | N/A (non-drug) | Recruiting | 2026-03-03 | 2026-08-03 (est.) | 45 | Egypt | Female | 2026-08-06 |
| NCT07242430 ClinicalTrials.gov |
12-week Multi-vitamin/Mineral Supplementation on Peri-menopause Symptoms, Cognition, Sleep, and Psychological Well-being. Updated ≤90d | Northumbria University | N/A (non-drug) | Active, not recruiting | 2026-04-07 | 2026-10-25 (est.) | 58 | United Kingdom | Female | 2026-08-05 |
| NCT06678880 ClinicalTrials.gov |
Sleep and Light Intervention (SALI) for Menopausal Mood Dysfunction Updated ≤90d | University of California, San Diego | N/A (non-drug) | Recruiting | 2025-03-11 | 2028-12 (est.) | 120 | United States | Female | 2026-08-05 |
| NCT07235878 ClinicalTrials.gov |
12-week Magnesium Supplementation on Peri-menopause Symptoms, Cognition, Sleep, and Psychological Well-being Updated ≤90d | Northumbria University | N/A (non-drug) | Active, not recruiting | 2025-12-09 | 2026-10-18 (est.) | 58 | United Kingdom | Female | 2026-08-05 |
| NCT06978504 ClinicalTrials.gov |
Impact of Genetic Polymorphisms And DASH Diet On Weight Loss Progression In Climacteric Women With Metabolic Syndrome Updated ≤90d | Nutrindo Ideais Research Center | N/A (non-drug) | Completed | 2025-04-01 | 2025-08-01 | 30 | Brazil | Female | 2026-08-04 |
| NCT07022340 ClinicalTrials.gov |
Hemodynamics After Resistance Training Updated ≤90d | University of Michigan | N/A (non-drug) | Recruiting | 2025-06-06 | 2026-12 (est.) | 50 | United States | Female | 2026-08-03 |
| NCT07742488 ClinicalTrials.gov |
Effects of Statins and Hormone Replacement Therapy in Coagulation Profile of Menopausal Women With Dyslipidemia NewUpdated ≤90d | University of Pisa | Observational | Recruiting | 2025-10-15 | 2029-12 (est.) | 70 | Italy | Female | 2026-08-03 |
| NCT07394049 ClinicalTrials.gov |
A Prospective Multicenter Cohort Study of Contemporary Menopausal Hormone Therapy and Cardiovascular Outcomes Updated ≤90d | Heinrich-Heine University, Duesseldorf | Observational | Not yet recruiting | 2026-08-01 (est.) | 2041-03 (est.) | 3,408 | Germany | Female | 2026-07-31 |
| NCT07738211 ClinicalTrials.gov |
Laughter Yoga, Emotional Labor, and Menopause-Specific Quality of Life in Nurses NewUpdated ≤90d | Inonu University | N/A (non-drug) | Active, not recruiting | 2025-07-25 | 2026-07-25 | 120 | Turkey (Türkiye) | Female | 2026-07-31 |
| NCT07739615 ClinicalTrials.gov |
Effect of Soya Bean on the Female Reproductive Hormones and Menopausal Symptoms NewUpdated ≤90d | Alex Ekwueme Federal University Teaching Hospital | N/A (non-drug) | Not yet recruiting | 2026-08-01 (est.) | 2026-08-30 (est.) | 69 | — | Female | 2026-07-31 |
| NCT07737613 ClinicalTrials.gov |
Acute Effects of Estradiol Administration on Brain Function During Fear Learning NewUpdated ≤90d | University of Arizona | Early Phase 1 | Not yet recruiting | 2026-08 (est.) | 2027-08 (est.) | 30 | — | Female | 2026-07-30 |
| NCT07737691 ClinicalTrials.gov |
Relaxation Training Via Tele-Rehabilitation in Postmenopausal Women NewUpdated ≤90d | Marmara University | N/A (non-drug) | Not yet recruiting | 2026-08-01 (est.) | 2026-09-20 (est.) | 30 | — | Female | 2026-07-30 |
| NCT07737782 ClinicalTrials.gov |
Retrospective Cohort Study of Symptoms and Quality of Life in Women With Genitourinary Syndrome of Menopause. NewUpdated ≤90d | Mucosa Innovations, S.L. | Observational | Not yet recruiting | 2026-07 (est.) | 2026-09 (est.) | 100 | Spain | Female | 2026-07-30 |
| NCT07705724 ClinicalTrials.gov |
Effect Of Whole or Skimmed Milk Greek Yogurt on Integrated Muscle Protein Synthesis, Glucose Homeostasis, and Cognition in Post-Menopausal Women Updated ≤90d | University of Arkansas | N/A (non-drug) | Not yet recruiting | 2026-10-01 (est.) | 2028-10-01 (est.) | 40 | United States | Female | 2026-07-30 |
| NCT07732452 ClinicalTrials.gov |
Hormone thERapy Effects on BRAin-HEART Health During the Menopausal Transition NewUpdated ≤90d | McGill University Health Centre/Research Institute of the McGill University Health Centre | Phase 4 | Not yet recruiting | 2026-11 (est.) | 2028-11 (est.) | 100 | — | Female | 2026-07-29 |
| NCT07729930 ClinicalTrials.gov |
Dietary Supplements and Middle Aged Women (Creatine) NewUpdated ≤90d | Loughborough University | N/A (non-drug) | Recruiting | 2026-05-01 | 2028-11-01 (est.) | 38 | United Kingdom | Female | 2026-07-28 |
| NCT07596069 ClinicalTrials.gov |
Prevalence of Menopause-associated Symptoms Throughout the Menopausal Transition in Women Aged 40 to 70 Residing in Spain and Its Relationship With Physical Activity - MdH Study Updated ≤90d | Cuerpos Serranos S.L. | Observational | Recruiting | 2026-04-18 | 2026-09 (est.) | 15,000 | Spain | Female | 2026-07-28 |
| NCT07628790 ClinicalTrials.gov |
Feasibility of Lower-Body EMS Resistance Training in Postmenopausal Women Updated ≤90d | Seoul National University | N/A (non-drug) | Completed | 2026-06-01 | 2026-07-27 | 16 | South Korea | Female | 2026-07-28 |
| NCT07526948 ClinicalTrials.gov |
Vaginal Estradiol vs Moisturizer to Improve Postmenopausal Vaginal Aging Symptoms and the Microbiome in Women Living With HIV Updated ≤90d | Albert Einstein College of Medicine | Phase 4 | Not yet recruiting | 2026-09 (est.) | 2029-09-30 (est.) | 62 | United States | Female | 2026-07-28 |
| NCT07728461 ClinicalTrials.gov |
Menopause and Compassionate Living Education NewUpdated ≤90d | Ataturk University | N/A (non-drug) | Not yet recruiting | 2026-09-30 (est.) | 2026-12-15 (est.) | 68 | Turkey (Türkiye) | Female | 2026-07-27 |
| NCT07365514 ClinicalTrials.gov |
Blackcurrants Modify Gut Microbiota and Reduce Osteoporosis Risk in Postmenopausal Females Updated ≤90d | University of Connecticut | Phase 1 | Recruiting | 2026-07 (est.) | 2028-02 (est.) | 159 | United States | Female | 2026-07-23 |
| NCT06673004 ClinicalTrials.gov |
Ovarian Tissue Allo-transplantation Updated ≤90d | University Hospitals Cleveland Medical Center | N/A (non-drug) | Not yet recruiting | 2026-09-01 (est.) | 2030-05-30 (est.) | 10 | United States | Female | 2026-07-23 |
| NCT07713862 ClinicalTrials.gov |
Midlife Empowerment and Longevity Through Optimizing Wellness Updated ≤90d | National University Health System, Singapore | N/A (non-drug) | Not yet recruiting | 2027-01 (est.) | 2029-01 (est.) | 200 | — | Female | 2026-07-23 |
| NCT07401810 ClinicalTrials.gov |
Fascial Yoga in Menopausal Women | Marmara University | N/A (non-drug) | Not yet recruiting | 2026-07-01 (est.) | 2026-09-01 (est.) | 60 | — | Female | 2026-07-22 |
| NCT06975111 ClinicalTrials.gov |
Focusing on the Menopausal Transition to Improve Mid-Life Women's Health | University of Colorado, Denver | Phase 2/3 | Recruiting | 2026-03-01 | 2029-10-31 (est.) | 200 | United States | Female | 2026-07-21 |
| NCT06480695 ClinicalTrials.gov |
Exercise Training Intensity and Nitrate Supplementation in Post-Menopausal Females | University of Virginia | N/A (non-drug) | Recruiting | 2025-07-01 | 2026-12-31 (est.) | 40 | United States | Female | 2026-07-17 |
| NCT07615777 ClinicalTrials.gov |
Nutritional Supplementation on Physiological and Metabolic Markers in Females | University of Southampton | N/A (non-drug) | Recruiting | 2026-07-09 | 2026-12 (est.) | 80 | United Kingdom | Female | 2026-07-13 |
| NCT07697768 ClinicalTrials.gov |
Photobiomodulation for Vaginal Dysfunctions: Home-Based vs Outpatient Treatment | Patricia Lordelo | N/A (non-drug) | Not yet recruiting | 2026-07-30 (est.) | 2027-06-30 (est.) | 150 | Brazil | Female | 2026-07-13 |
| NCT07695376 ClinicalTrials.gov |
CARAMEL Observational Study | Biogipuzkoa Health Research Institute | Observational | Recruiting | 2026-03-16 | 2028-05 (est.) | 3,000 | Colombia, Croatia, Greece +2 | Female | 2026-07-10 |
| NCT07690137 ClinicalTrials.gov |
Pelvic Floor Symptoms Across Menopausel Stages | Bezmialem Vakif University | Observational | Not yet recruiting | 2026-07-06 (est.) | 2026-09-06 (est.) | 180 | Turkey (Türkiye) | Female | 2026-07-09 |
| NCT06743269 ClinicalTrials.gov |
Time-Efficient Inspiratory Muscle Strength Training for Reducing Sympathetic Activity and Improving Sleep in Midlife Women | Mayo Clinic | N/A (non-drug) | Recruiting | 2025-03-27 | 2027-01-01 (est.) | 30 | United States | Female | 2026-07-09 |
| NCT03916978 ClinicalTrials.gov |
Autologous PRP Intra Ovarian Infusion to Restore Ovarian Function in Menopausal Women | Genesis Athens Clinic | Phase 2/3 | Recruiting | 2019-05-21 | 2027-01-30 (est.) | 100 | Greece | Female | 2026-07-08 |
| NCT06889753 ClinicalTrials.gov |
A Clinical Trial to Investigate the Effect of Pollen Extracts on Menopausal Symptoms in Healthy Women. | Graminex LLC | Phase 2 | Recruiting | 2025-10-29 | 2026-08 (est.) | 120 | Canada | Female | 2026-07-08 |
| NCT04031456 ClinicalTrials.gov |
Autologous PRP Infusion May Restore Ovarian Function and May Promote Folliculogenesis in POI Patients | Genesis Athens Clinic | Phase 2/3 | Recruiting | 2019-07-30 | 2027-01-30 (est.) | 100 | Greece | Female | 2026-07-08 |
| NCT07676604 ClinicalTrials.gov |
Colipral® (Probiotic Strain Escherichia Coli 5C (ECP24®)) for Prevention of Recurrent Cystitis in Menopausal Women | Liaquat University of Medical & Health Sciences | N/A (non-drug) | Not yet recruiting | 2026-07-06 (est.) | 2027-07-31 (est.) | 134 | — | Female | 2026-07-06 |
| NCT07679074 ClinicalTrials.gov |
CREST: Samphire Guided Care Program on Wellbeing, Work Productivity, and Quality of Life | Samphire Group, Inc. | Observational | Recruiting | 2026-06-01 | 2027-01-01 (est.) | 50 | United States | Female | 2026-07-01 |
| NCT07678359 ClinicalTrials.gov |
Effect of ZenRest™ Lotus Seed & Rice Germ Extract Blend on Sleep Quality in Menopausal Women | Nutraland USA, Inc. | N/A (non-drug) | Not yet recruiting | 2026-07 (est.) | 2026-09 (est.) | 60 | United States | Female | 2026-07-01 |
| NCT07486986 ClinicalTrials.gov |
Endocrine Disruption, Menopause, and Poor Sleep in wOmen With Type 2 Diabetes: Effects on Cardiovascular Health | Ottawa Heart Institute Research Corporation | Observational | Not yet recruiting | 2026-09 (est.) | 2032-12 (est.) | 381 | — | Female | 2026-07-01 |
| NCT07427459 ClinicalTrials.gov |
Amygdala Insula Retraining in the Management of Perimenopause Symptoms | Chronic Conditions Research Fund | N/A (non-drug) | Recruiting | 2026-07-15 (est.) | 2027-01-31 (est.) | 160 | United States | Female | 2026-06-29 |
| NCT07672548 ClinicalTrials.gov |
The Effects of 10-weeks Pilates Exercise on Pulmonary Function and Quality of Life in Postmenopausal Women | Middle East University | N/A (non-drug) | Recruiting | 2026-06-01 | 2026-07-01 (est.) | 30 | Jordan | Female | 2026-06-29 |
| NCT07657429 ClinicalTrials.gov |
Effect of Mandala Coloring on Menopausal Attitude, Perceived Stress and Mindfulness | Ondokuz Mayıs University | N/A (non-drug) | Not yet recruiting | 2026-05-30 (est.) | 2026-09-30 (est.) | 140 | Turkey (Türkiye) | Female | 2026-06-29 |
| NCT07158021 ClinicalTrials.gov |
Leuprolide and Goserelin for Ovarian Function Suppression in Pre- or Peri-menopausal Women With Breast Cancer, OFS Trial | University of Michigan Rogel Cancer Center | Phase 2 | Recruiting | 2026-01-22 | 2028-01-01 (est.) | 75 | United States | Female | 2026-06-23 |
| NCT07314827 ClinicalTrials.gov |
Women's Healthy Aging and Menopause; (WHAM) | University of Miami | N/A (non-drug) | Not yet recruiting | 2026-10-01 (est.) | 2028-01-31 (est.) | 60 | United States | Female | 2026-06-23 |
| NCT07657078 ClinicalTrials.gov |
Meleis' Transition Theory-Based Education and Counseling Program in Menopausal Women | Ankara Medipol University | N/A (non-drug) | Not yet recruiting | 2026-06-15 (est.) | 2026-10-15 (est.) | 114 | Turkey (Türkiye) | Female | 2026-06-22 |
| NCT07649356 ClinicalTrials.gov |
Significance of Estrogen Status for Muscle Function, Physical Fitness, and Physiological Health Parameters - a Comparison of Age-matched Groups of Women Before and After Menopause. | Mette Hansen | Observational | Recruiting | 2026-02-01 | 2027-08-01 (est.) | 30 | Denmark | Female | 2026-06-16 |
| NCT07648667 ClinicalTrials.gov |
Cognitive Task Sensitivity in Perimenopause and Nutritional Status | Northumbria University | Observational | Not yet recruiting | 2026-06 (est.) | 2026-07 (est.) | 60 | United Kingdom | Female | 2026-06-15 |
| NCT07648680 ClinicalTrials.gov |
"Menopause Experiences in Cultural and Intercultural Contexts" | Institut Investigacio Sanitaria Pere Virgili | Observational | Recruiting | 2026-04-27 | 2028-04-22 (est.) | 25 | Spain | Female | 2026-06-15 |
| NCT05193968 ClinicalTrials.gov |
Hot Flashes and Neurovascular Function in Women | Mayo Clinic | N/A (non-drug) | Recruiting | 2022-02-24 | 2026-12 (est.) | 120 | United States | Female | 2026-06-12 |
| NCT07635017 ClinicalTrials.gov |
Assessing the Effects of Hormones on Noninvasive Transcranial Stimulation | Carnegie Mellon University | N/A (non-drug) | Not yet recruiting | 2026-07-01 (est.) | 2028-05-01 (est.) | 25 | United States | All | 2026-06-09 |
| NCT07136415 ClinicalTrials.gov |
Comparing Digital Therapy, Trazodone, and Daridorexant for Menopause-Related Insomnia Symptoms | Brigham and Women's Hospital | Phase 4 | Recruiting | 2026-02-13 | 2031-02 (est.) | 1,000 | United States | Female | 2026-06-08 |
| NCT06527248 ClinicalTrials.gov |
Nitrate, Exercise and Vascular Function in Midlife Women | University of Vienna | N/A (non-drug) | Recruiting | 2025-03-31 | 2027-03 (est.) | 54 | Austria | Female | 2026-06-05 |
| NCT06917313 ClinicalTrials.gov |
FLASH-Breast: Evaluating the Efficacy of Fezolinetant in Reducing Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy | Yale University | Phase 2 | Recruiting | 2025-12-05 | 2028-03 (est.) | 92 | United States | Female | 2026-06-02 |
| NCT07618039 ClinicalTrials.gov |
MOving Forward With MENopause Treatment Through Pharmacists' Expanded Roles in Hormone Health | Dalhousie University | Observational | Not yet recruiting | 2026-07-01 (est.) | 2027-07-01 (est.) | 200 | — | Female | 2026-06-01 |
| NCT07075133 ClinicalTrials.gov |
Chrono-restricted Diet and Physical Activity as a New Preventive Strategy for Sarcopenia in Postmenopausal Women With Obesity and Type 2 Diabetes | University Hospital, Toulouse | N/A (non-drug) | Not yet recruiting | 2026-09-15 (est.) | 2029-07-15 (est.) | 45 | France | All | 2026-06-01 |
| NCT07617454 ClinicalTrials.gov |
Effects of Estrogen on Muscle Gain During 12-weeks of Exercise in Post-menopausal Women | Mette Hansen | N/A (non-drug) | Recruiting | 2026-02-01 | 2027-08-01 (est.) | 30 | Denmark | Female | 2026-06-01 |
| NCT07616401 ClinicalTrials.gov |
MicroRNA and Markers and Therapeutic Response to Romosozumab and Abaloparatide in Postmenopausal Osteoporosis | Istituto Auxologico Italiano | N/A (non-drug) | Recruiting | 2025-08-31 | 2029-08-31 (est.) | 42 | Italy | Female | 2026-06-01 |
| NCT07615790 ClinicalTrials.gov |
Structured Combined Exercise Program in Postmenopausal Women: Effects on Heart Rate Variability and Menopausal Symptoms | Fenerbahce University | N/A (non-drug) | Recruiting | 2026-04-27 | 2026-07 (est.) | 40 | Turkey (Türkiye) | Female | 2026-05-29 |
| NCT07614542 ClinicalTrials.gov |
AGEWISE: Unravelling the Gut-Hormone Axis in Women's Ageing | Gulbenkian Institute for Molecular Medicine | Observational | Recruiting | 2025-06-02 | 2026-12 (est.) | 300 | Portugal | Female | 2026-05-29 |
| NCT07606326 ClinicalTrials.gov |
A Retrospective and Prospective Clinical Registry for Data Collection of Perimenopausal, Menopausal and Premature Ovarian Insufficiency Women | IRCCS San Raffaele | Observational | Not yet recruiting | 2026-06 (est.) | 2040-12 (est.) | 5,000 | — | Female | 2026-05-26 |
| NCT07602530 ClinicalTrials.gov |
A Study in Canada to Follow Outcomes of Women in Menopause Treated With Fezolinetant for Hot Flashes, When Given in Clinical Practice | Astellas Pharma Europe Ltd. | Observational | Recruiting | 2025-10-23 | 2027-02-28 (est.) | 238 | Canada | Female | 2026-05-22 |
| NCT06856174 ClinicalTrials.gov |
Menopausal HT for Women Living With HIV (HoT) | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | Phase 4 | Recruiting | 2026-04-09 | 2027-09-20 (est.) | 105 | United States | Female | 2026-05-22 |
| NCT07603089 ClinicalTrials.gov |
Exploring the Link Between Menopause, Glucose Control, and Frozen Shoulder in Women | University of Nottingham | Observational | Not yet recruiting | 2026-08 (est.) | 2027-09 (est.) | 340 | — | Female | 2026-05-22 |
| NCT07597915 ClinicalTrials.gov |
Our Transitions: Improving the Path to Menopause With Personal Digital Health Technologies | 4YouandMe | Observational | Not yet recruiting | 2026-05-01 (est.) | 2027-08-31 (est.) | 1,250 | — | Female | 2026-05-20 |
| NCT07077395 ClinicalTrials.gov |
Finding Links Between Hot flASHes and CardioVascular Disease | Massachusetts General Hospital | Phase 2 | Recruiting | 2026-03-01 | 2029-06 (est.) | 80 | United States | Female | 2026-05-20 |
| NCT06490146 ClinicalTrials.gov |
Menopause Transition, Sex Hormone Deficiency and Autonomic and Vascular Function | University of Minnesota | Observational | Recruiting | 2025-04-01 | 2030-08-21 (est.) | 100 | United States | Female | 2026-05-20 |
| NCT07477483 ClinicalTrials.gov |
Effect of Manuel Therapy on Tension Type Headache in Menopausal and Premenopasual Women | Necmettin Erbakan University | N/A (non-drug) | Recruiting | 2025-10-01 | 2026-05 (est.) | 50 | Turkey (Türkiye) | Female | 2026-05-20 |
| NCT07600567 ClinicalTrials.gov |
Algal Lutein Against Decline of Intellectual Nimbleness | Poznan University of Life Sciences | N/A (non-drug) | Not yet recruiting | 2026-05-01 (est.) | 2027-04-30 (est.) | 300 | Poland | Female | 2026-05-20 |
| NCT07599319 ClinicalTrials.gov |
Avatar-Based Education and Counseling for Spousal Support During Menopause | Eskisehir Osmangazi University | N/A (non-drug) | Recruiting | 2025-07-15 | 2026-12-15 (est.) | 280 | Turkey (Türkiye) | All | 2026-05-20 |
| NCT07599930 ClinicalTrials.gov |
Impact of a Novel Functional Snack on Perimenopausal Symptoms and Well-being | King's College London | N/A (non-drug) | Recruiting | 2026-04-24 | 2026-12 (est.) | 20 | United Kingdom | Female | 2026-05-20 |
| NCT07596368 ClinicalTrials.gov |
THE EFFECT OF MOTIVATIONAL INTERVIEWING ON MENOPAUSE MYTHS AND POSTTRAUMATIC GROWTH IN POSTMENOPAUSAL WOMEN:RANDOMIZED CONTROLLED STUDY | Inonu University | N/A (non-drug) | Not yet recruiting | 2026-05 (est.) | 2026-10 (est.) | 96 | — | Female | 2026-05-19 |
| NCT06419972 ClinicalTrials.gov |
Multimodal Program for Climacteric Women | University of Valencia | N/A (non-drug) | Recruiting | 2024-05-30 | 2026-10-25 (est.) | 115 | Spain | Female | 2026-05-19 |
| NCT07590999 ClinicalTrials.gov |
Probiotic Intake and Perimenopausal Psychological Assessments | University of Oxford | N/A (non-drug) | Recruiting | 2025-11-12 | 2027-06-30 (est.) | 106 | United Kingdom | Female | 2026-05-15 |
| NCT06982677 ClinicalTrials.gov |
Improving Outcomes in Early Menopause After Cancer | Duke University | N/A (non-drug) | Recruiting | 2026-01-20 | 2027-05 (est.) | 117 | United States | Female | 2026-05-14 |
| 2023-506211-18-00 EU CTIS |
PROPOSE: Effect of Intravaginal Prasterone on Genitourinary Syndrome in Women in Menopause with previous Breast Cancer or currently under treatment with endocrine therapy for Breast Cancer with aromatase inhibitor +/- LHRHa | Istituto Europeo Di Oncologia S.r.l. | Phase 3 | Ongoing, recruiting | 2025-01-09 | — | — | Italy | Female | 2026-05-14 |
| NCT07584109 ClinicalTrials.gov |
The Effect of Value Clarification Based on Meleis's Transition Theory on Menopausal Symptoms, Depression, Anxiety, Stress, and Quality of Life in Perimenopausal Women | Ordu University | N/A (non-drug) | Not yet recruiting | 2026-05-04 (est.) | 2026-08-04 (est.) | 88 | Turkey (Türkiye) | Female | 2026-05-13 |
| NCT07580846 ClinicalTrials.gov |
ATENEA Study: Adherence to Creatine-Based Nutritional Supplementation in Estrogen-Depleted Women | Margan Biotech | Observational | Recruiting | 2026-03-20 | 2026-10-01 (est.) | 100 | Spain | Female | 2026-05-12 |
| NCT07577297 ClinicalTrials.gov |
Comparative Effects of Kinesio Taping on Cervical Pain in Climacteric Women | University of Valencia | N/A (non-drug) | Not yet recruiting | 2026-05-20 (est.) | 2026-09-01 (est.) | 50 | — | Female | 2026-05-11 |
| NCT07341087 ClinicalTrials.gov |
Skin Inflammation in (Peri)Menopause: A Probiotic Intervention Proof of Concept Trial | King's College London | N/A (non-drug) | Recruiting | 2026-04-28 | 2027-11-01 (est.) | 30 | United Kingdom | Female | 2026-05-08 |
| NCT05251324 ClinicalTrials.gov |
The Cardiovascular Impact of Hot Flushes | University of Minnesota | Observational | Recruiting | 2022-03-01 | 2027-05-26 (est.) | 60 | United States | Female | 2026-05-07 |
| NCT07572981 ClinicalTrials.gov |
Study of the Effectiveness of Clinical Hypnosis and Self-hypnosis in Relieving Hot Flashes in Menopausal Women | University Hospital, Toulouse | N/A (non-drug) | Not yet recruiting | 2026-06-01 (est.) | 2026-12-31 (est.) | 94 | France | Female | 2026-05-07 |
| NCT07406412 ClinicalTrials.gov |
Hormonal Regulation of Cardiometabolic Health Study | University of Jyvaskyla | Observational | Recruiting | 2026-02-13 | 2028-12-15 (est.) | 120 | Finland | Female | 2026-05-06 |
| NCT07570732 ClinicalTrials.gov |
Occupational Disruption and Role Strain During Perimenopause | Russell Sage College | Observational | Not yet recruiting | 2026-06-01 (est.) | 2026-12-01 (est.) | 100 | United States | Female | 2026-05-06 |
| NCT07563621 ClinicalTrials.gov |
Determining the Extent of the Genitourinary Syndrome of Menopause Burden in Breast Cancer Survivors | Jessa Hospital | Observational | Recruiting | 2026-03-05 | 2028-03-06 (est.) | 264 | Belgium | Female | 2026-05-04 |
| NCT07500922 ClinicalTrials.gov |
Menopause Effects on Cortico-reticular Functioning | University of Jyvaskyla | N/A (non-drug) | Recruiting | 2026-04-25 | 2027-12-31 (est.) | 20 | Finland | Female | 2026-05-01 |
| NCT05331209 ClinicalTrials.gov |
Acupuncture With/Without Self-acupressure for Post-oophorectomy Hot Flashes in BRCA Carriers | Shaare Zedek Medical Center | N/A (non-drug) | Not yet recruiting | 2026-12-01 (est.) | 2028-12-31 (est.) | 200 | Israel | Female | 2026-04-29 |
| NCT06873971 ClinicalTrials.gov |
Er:YAG Laser Combined With Vaginal Estriol for Genitourinary Syndrome of Menopause | University of Nove de Julho | N/A (non-drug) | Recruiting | 2025-12-10 | 2026-11-10 (est.) | 60 | Brazil | Female | 2026-04-23 |
| NCT07284082 ClinicalTrials.gov |
The Synergistic Effects of Menopause and HIV on Cardiovascular Disease Risk in Women | University of California, San Francisco | Observational | Recruiting | 2026-04-17 | 2030-03-01 (est.) | 90 | United States | Female | 2026-04-22 |
| NCT07538167 ClinicalTrials.gov |
Food Trial Evaluating Fecal Abundance of SBD111 With Once-Daily Versus Twice-Daily Administration in Healthy Adults | Solarea Bio, Inc | N/A (non-drug) | Not yet recruiting | 2026-04 (est.) | 2027-01 (est.) | 80 | — | All | 2026-04-20 |
| NCT07131215 ClinicalTrials.gov |
Smart Technology-Based Intervention and Monitoring of Physical and Mental Health in Early Postmenopausal Women | YI-JU TSAI | N/A (non-drug) | Recruiting | 2025-08-15 | 2028-07-30 (est.) | 90 | Taiwan | Female | 2026-04-14 |
| NCT07402382 ClinicalTrials.gov |
Effects of Amylopectin Chromium Blend on Whole-Body Protein Kinetics and Glucose in Peri/Post-Menopausal Women | Nutrition 21, Inc. | N/A (non-drug) | Recruiting | 2025-11-01 | 2026-06-30 (est.) | 60 | United States | Female | 2026-04-13 |
| NCT06962345 ClinicalTrials.gov |
Changes in the Impact of Genitourinary Syndrome of Menopause With a Novel Nonhormonal Vulvovaginal Gel Assessed by PROMs. | Mucosa Innovations, S.L. | N/A (non-drug) | Recruiting | 2024-01-08 | 2026-12 (est.) | 80 | Spain | Female | 2026-03-30 |
| NCT07501377 ClinicalTrials.gov |
Effects of a 6-months Fiber- and Polyphenol-rich Diet on Brain Inflammatory Processes in Perimenopausal Women Living With Overweight or Obesity | Max Planck Institute for Human Cognitive and Brain Sciences | N/A (non-drug) | Recruiting | 2026-03-19 | 2029-06-30 (est.) | 120 | Germany | Female | 2026-03-30 |
| NCT07497191 ClinicalTrials.gov |
AMH Dynamic Changes to Predict Ovarian Reserve in Perimenopausal Breast Cancer | Shengjing Hospital | Observational | Not yet recruiting | 2026-03-05 (est.) | 2029-03-05 (est.) | 300 | — | Female | 2026-03-27 |
| NCT07420218 ClinicalTrials.gov |
Menopausal Hormones and Sympathetic Activation | University of Delaware | Phase 4 | Not yet recruiting | 2026-09-01 (est.) | 2030-06-01 (est.) | 80 | — | Female | 2026-03-27 |
| NCT07135232 ClinicalTrials.gov |
The Effects of Resistance Training and a Plant-Based Supplement on Perimenopausal Symptoms and Muscle Health. | Leeds Beckett University | N/A (non-drug) | Recruiting | 2026-03-01 (est.) | 2027-03-01 (est.) | 72 | United Kingdom | Female | 2026-03-27 |
| NCT07496294 ClinicalTrials.gov |
Comparison of Oral Dydrogesterone and Vaginal Progesterone in Menopausal Hormone Therapy | Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital | N/A (non-drug) | Not yet recruiting | 2026-04 (est.) | 2027-10 (est.) | 200 | Turkey (Türkiye) | Female | 2026-03-27 |
| NCT07472881 ClinicalTrials.gov |
Multi-Acupoint Laser Therapy for Body Shape and Composition in Obese Menopausal Women | Chang Gung Memorial Hospital | N/A (non-drug) | Recruiting | 2026-03-16 | 2029-01-24 (est.) | 40 | Taiwan | Female | 2026-03-20 |
| NCT06318403 ClinicalTrials.gov |
Estradiol Supplementation and Rotator Cuff Repair | University of Utah | Phase 2 | Not yet recruiting | 2028-03 (est.) | 2030-12 (est.) | 58 | — | Female | 2026-03-19 |
| NCT07294339 ClinicalTrials.gov |
A Randomized Controlled Trial of Acupuncture for the Management of Hot Flashes in Patients With Hormone Receptor-Positive Breast Cancer | Peking University People's Hospital | N/A (non-drug) | Not yet recruiting | 2026-04-01 (est.) | 2027-08-01 (est.) | 60 | China | Female | 2026-03-19 |
| NCT07481513 ClinicalTrials.gov |
Impact of Intermittent Fasting on the Mental Health of Perimenopausal Women | American University of Beirut Medical Center | N/A (non-drug) | Recruiting | 2025-09-23 | 2026-06 (est.) | 140 | Lebanon | Female | 2026-03-19 |
| NCT07229976 ClinicalTrials.gov |
Clinical Efficacy of Thumbtack Needle for Chronic Insomnia in Perimenopausal and Menopausal Women | Huazhong University of Science and Technology | N/A (non-drug) | Not yet recruiting | 2026-03-20 (est.) | 2029-12-30 (est.) | 198 | — | Female | 2026-03-17 |
| NCT07393672 ClinicalTrials.gov |
Effects of Hemp-Derived Cannabinoids on Menopause Symptoms | Washington State University | Phase 2 | Recruiting | 2026-02-11 | 2026-11-10 (est.) | 104 | United States | Female | 2026-03-10 |
| NCT01530373 ClinicalTrials.gov |
Solifenacin Compared to Clonidine for Reducing Hot Flashes Among Breast Cancer Patients | University of Arkansas | Phase 2 | Recruiting | 2012-02 | 2027-07 (est.) | 110 | United States | Female | 2026-03-05 |
| NCT07447947 ClinicalTrials.gov |
Lived Experience and Perceptions of Menopause Among Patients Participating in the Multidisciplinary Care Pathways at Paris Saint-Joseph Hospital | Fondation Hôpital Saint-Joseph | Observational | Not yet recruiting | 2026-05 (est.) | 2026-11 (est.) | 24 | France | Female | 2026-03-04 |
| NCT07441109 ClinicalTrials.gov |
Shatavari Root Extract for Perimenopausal Symptoms | SF Research Institute, Inc. | N/A (non-drug) | Not yet recruiting | 2026-03-11 (est.) | 2026-06-15 (est.) | 60 | United States | Female | 2026-03-03 |
| NCT07443644 ClinicalTrials.gov |
Targeting Insomnia to Prevent Depression in the Menopause Transition | SRI International | N/A (non-drug) | Not yet recruiting | 2026-09 (est.) | 2031-02 (est.) | 230 | — | Female | 2026-03-02 |
| NCT07435545 ClinicalTrials.gov |
Effect of Laughter Yoga on Menopausal Symptoms, Sleep, and Quality of Life in Menopausal Women | Saglik Bilimleri Universitesi | N/A (non-drug) | Not yet recruiting | 2026-03-01 (est.) | 2026-03-29 (est.) | 80 | Turkey (Türkiye) | Female | 2026-03-02 |
| NCT07254429 ClinicalTrials.gov |
COMPASS - COpenhagen MenoPAuSe Study | Martin Blomberg Jensen | Phase 2 | Recruiting | 2025-10-02 | 2027-12 (est.) | 192 | Denmark | Female | 2026-03-02 |
| 2023-507782-25-00 EU CTIS |
Efficacy of endothelin receptor antagonism in treatment of coronary artery spasm: a randomized controlled clinical trial. | Stichting Radboud University Medical Center | Phase 3 | Ongoing, recruiting | 2024-09-27 | — | — | Netherlands | Female, Male | 2026-02-25 |
| NCT05672901 ClinicalTrials.gov |
Silicone Gel vs. Estrogen Vaginal Cream for the Management of Genitourinary Syndrome of Menopause | Stratpharma AG | N/A (non-drug) | Recruiting | 2023-04-04 | 2026-09 (est.) | 100 | United States | Female | 2026-02-20 |
| NCT05953090 ClinicalTrials.gov |
VALOR: Vaginal Atrophy & Long-term Observation of Recovery | Stratpharma AG | N/A (non-drug) | Recruiting | 2023-10-30 | 2028-06 (est.) | 2,000 | United States | Female | 2026-02-20 |
| NCT07423143 ClinicalTrials.gov |
Menopausal Impact of Opportunistic Salpingectomy for Ovarian Cancer Prevention | Umeå University | N/A (non-drug) | Not yet recruiting | 2026-03 (est.) | 2029-02 (est.) | 2,100 | Sweden | Female | 2026-02-20 |
| NCT07419542 ClinicalTrials.gov |
Effect of High Power Laser Acupuncture on Post Menopausal Hot Flashes | Cairo University | N/A (non-drug) | Not yet recruiting | 2026-02-20 (est.) | 2026-04-20 (est.) | 60 | Egypt | Female | 2026-02-19 |
| NCT07417709 ClinicalTrials.gov |
Interest of Adaptated Physical Activity (APA) on the K Recovery Constant, Reflecting the Rate of Muscle Oxygenation Recovery in Menopausal Women Suffering From Depression | Centre Hospitalier Universitaire de Besancon | N/A (non-drug) | Not yet recruiting | 2026-02 (est.) | 2028-10 (est.) | 52 | France | Female | 2026-02-18 |
| NCT07419035 ClinicalTrials.gov |
Bipolar Radiofrequency for Genitourinary Syndrome of Menopause | University of Castilla-La Mancha | N/A (non-drug) | Not yet recruiting | 2026-03-15 (est.) | 2026-09-30 (est.) | 40 | Spain | Female | 2026-02-18 |
| NCT06691178 ClinicalTrials.gov |
Vaginal Changes After CO2 Laser | University of California, Irvine | N/A (non-drug) | Recruiting | 2023-05-01 | 2027-05-01 (est.) | 50 | United States | Female | 2026-02-18 |
| NCT07417228 ClinicalTrials.gov |
The Impact of Concurrent Training on Women Experiencing Symptoms of Menopause Ireland | University College Dublin | N/A (non-drug) | Recruiting | 2025-12-12 | 2027-12-01 (est.) | 90 | Ireland | Female | 2026-02-18 |
| NCT07413705 ClinicalTrials.gov |
BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Sexual Function Among Perimenopausal and Postmenopausal Women | BTL Industries Ltd. | N/A (non-drug) | Recruiting | 2025-11-20 | 2026-12-11 (est.) | 60 | Canada, United States | Female | 2026-02-17 |
| 2023-507847-13-00 EU CTIS |
A randomized intrapatient cross-over study to assess the efficacy of oxybutynin versus venlafaxine in REDucing hot FLASHes in women using endocrine therapy after breast cancer: the RED FLASH study. | Reinier de Graaf Groep | Phase 3 | Ongoing, recruiting | 2024-08-09 | — | — | Netherlands | Female | 2026-02-16 |
| NCT06965686 ClinicalTrials.gov |
Development of a Personalized, Psychosocial Intervention for Menopausal Individuals With Elevated Dementia Risk | University of Chicago | N/A (non-drug) | Recruiting | 2025-01-31 | 2026-12-30 (est.) | 60 | United States | Female | 2026-02-05 |
| NCT07165964 ClinicalTrials.gov |
Nursing Interventions to Enhance Positive Mental Health and Self Care in Women During the Climacteric | University of Barcelona | N/A (non-drug) | Recruiting | 2025-07-31 | 2026-07-01 (est.) | 250 | Spain | Female | 2026-02-05 |
| NCT07120997 ClinicalTrials.gov |
Prunes Preventing Bone Loss in Perimenopause | Penn State University | N/A (non-drug) | Recruiting | 2025-12-11 | 2029-09 (est.) | 124 | United States | Female | 2026-02-04 |
| NCT07376395 ClinicalTrials.gov |
Effects of Jin Shin Jyutsu-Based Hand Application on Quality of Life and Psychosocial Status in Perimenopausal Women | Istanbul University - Cerrahpasa | N/A (non-drug) | Not yet recruiting | 2026-02 (est.) | 2027-08 (est.) | 60 | Turkey (Türkiye) | Female | 2026-02-03 |
| NCT07378787 ClinicalTrials.gov |
Time-Restricted Eating in Combination With a Low Glycaemic Index Diet on Cognitive Function, Biological Ageing and Metabolic Health in Perimenopause and Menopause. | University of Nicosia | N/A (non-drug) | Recruiting | 2026-01-17 | 2029-01-20 (est.) | 72 | Croatia, Cyprus | Female | 2026-01-30 |
| NCT07375732 ClinicalTrials.gov |
Transcranial Electrical Stimulation for Noninvasive Study of Menopausal/Perimenopausal Symptoms | Carnegie Mellon University | N/A (non-drug) | Not yet recruiting | 2026-02 (est.) | 2026-12 (est.) | 50 | — | Female | 2026-01-29 |
| NCT06855784 ClinicalTrials.gov |
Time-Restricted Eating in Menopause and HOrmone-sensitive Breast Cancers (TREMHO) | University Hospital, Geneva | N/A (non-drug) | Recruiting | 2025-04-30 | 2027-03-01 (est.) | 84 | Switzerland | Female | 2026-01-27 |
| NCT06446869 ClinicalTrials.gov |
Menopausal Symptoms Probiotic Study | Community Pharmacology Services Ltd | N/A (non-drug) | Recruiting | 2024-09-10 | 2026-07-25 (est.) | 140 | United Kingdom | Female | 2026-01-26 |
| NCT07356479 ClinicalTrials.gov |
Enhancing Mental and Physical Health of Women Veterans 3.0 | VA Office of Research and Development | N/A (non-drug) | Not yet recruiting | 2026-10-01 (est.) | 2030-09-30 (est.) | 18 | United States | All | 2026-01-21 |
| NCT06999317 ClinicalTrials.gov |
CARAMEL: Retrospective Study for Personalized Risk Assessment of Cardiovascular Disease in Menopausal and Perimenopausal Women Using Real World Data | Hospital Universitario Virgen Macarena | Observational | Not yet recruiting | 2026-03-01 (est.) | 2027-12-01 (est.) | 1,500,000 | — | Female | 2026-01-15 |
| NCT07342400 ClinicalTrials.gov |
A Clinical Study to Assess Histological Changes From Treatment of Poly L-lactic Acid Biostimulator on Women at Various Menopausal Stages | Galderma R&D | N/A (non-drug) | Recruiting | 2025-08-12 | 2026-11 (est.) | 40 | United States | Female | 2026-01-15 |
| NCT06497894 ClinicalTrials.gov |
No More Sleepless Nights in Perimenopause | Insel Gruppe AG, University Hospital Bern | Phase 4 | Recruiting | 2026-01-01 | 2026-07-01 (est.) | 54 | Switzerland | Female | 2026-01-13 |
| NCT04439370 ClinicalTrials.gov |
Autonomic Regulation of Blood Pressure in Premature and Early Menopausal Women | University of Minnesota | Observational | Recruiting | 2019-10-01 | 2026-12-30 (est.) | 160 | United States | Female | 2026-01-08 |
| NCT07322250 ClinicalTrials.gov |
The Effect of Blood Flow Restriction Training on Postmenopausal Stress Urinary Incontinence | Kafrelsheikh University | N/A (non-drug) | Not yet recruiting | 2025-12-30 (est.) | 2026-06-15 (est.) | 60 | — | Female | 2026-01-07 |
| NCT07309692 ClinicalTrials.gov |
Different Modalities for the Evaluation of Patients With Peri-menopausal Bleeding | Sohag University | N/A (non-drug) | Recruiting | 2025-12-01 | 2026-08-31 (est.) | 106 | Egypt | Female | 2025-12-30 |
| NCT06343870 ClinicalTrials.gov |
Estradiol and Testosterone Subdermal Implants for Menopause Treatment (ESTIME) | University of Sao Paulo General Hospital | Phase 3 | Recruiting | 2025-12-18 | 2026-08-18 (est.) | 140 | Brazil | Female | 2025-12-29 |
| NCT07299903 ClinicalTrials.gov |
IMB-Based Sleep Hygiene Education for Menopausal Women: Effects on Sleep Quality and Depression | Ankara Yildirim Beyazıt University | N/A (non-drug) | Recruiting | 2026-01-01 (est.) | 2026-03-01 (est.) | 500 | Turkey (Türkiye) | Female | 2025-12-23 |
| NCT07251296 ClinicalTrials.gov |
Impact of Funcional Exercise and Supplementation in Perimenopausal Women's Health | University of Valencia | N/A (non-drug) | Recruiting | 2025-12-15 | 2026-07 (est.) | 90 | Spain | Female | 2025-12-22 |
| NCT07259525 ClinicalTrials.gov |
Escitalopram Plasma Concentrations in Premenopausal and Postmenopausal Women | Eskisehir Osmangazi University | Observational | Not yet recruiting | 2026-01 (est.) | 2028-01 (est.) | 94 | Turkey (Türkiye) | Female | 2025-12-22 |
| NCT07292857 ClinicalTrials.gov |
Comparing and Predicting the Risk of Respiratory Tract Infection (RTI) Among Post-menopausal Women on or Without Hormone Replacement Therapy (HRT): an Observational Cohort Study | Insel Gruppe AG, University Hospital Bern | Observational | Recruiting | 2024-09-18 | 2025-12 (est.) | 400 | Switzerland | Female | 2025-12-18 |
| 2025-523214-83-00 EU CTIS |
The effect of transdermal 17-β-estradiol/progesterone supplementation on glucose regulation in peri- and postmenopausal women with type 1 and type 2 diabetes | Amsterdam UMC Stichting | Phase 4 | Ongoing, recruiting | 2026-02-09 | — | — | Netherlands | Female | 2025-12-15 |
| NCT06376812 ClinicalTrials.gov |
No Time to Pause: Physical Activity to Improve Health of Midlife Hispanic Women | The University of Texas Medical Branch, Galveston | N/A (non-drug) | Not yet recruiting | 2027-01-20 (est.) | 2029-01 (est.) | 40 | United States | Female | 2025-12-08 |
| NCT07112651 ClinicalTrials.gov |
Efficacy of CL25216 on Vasomotor Symptoms in Women During Perimenopause | ApexCPG LLC | N/A (non-drug) | Recruiting | 2025-11-24 (est.) | 2026-06-12 (est.) | 80 | India | Female | 2025-12-05 |
| NCT07238478 ClinicalTrials.gov |
JDS-HF3.0 Supplementation on Menopause Related Quality of Life Outcomes in Postmenopausal Women | Bonafide Health | N/A (non-drug) | Recruiting | 2025-05-14 | 2026-07 (est.) | 250 | United States | Female | 2025-11-20 |
| NCT07052279 ClinicalTrials.gov |
Water Based Burpee Exercises on Functional Capacity in Poste-menopausal Women After Thyroidectomy | Al-Zaytoonah University of Jordan | N/A (non-drug) | Recruiting | 2025-09-01 | 2025-11-20 (est.) | 40 | Egypt | Female | 2025-11-19 |
| NCT06347926 ClinicalTrials.gov |
Study of Sexual Quality of Life in Women With Breast Cancer Who Had Multidisciplinary Management With Photobiomodulation for Genitourinary Syndrome of the Menopause | Institut du Cancer de Montpellier - Val d'Aurelle | N/A (non-drug) | Recruiting | 2025-03-13 | 2027-12 (est.) | 25 | France | Female | 2025-11-18 |
| NCT05831709 ClinicalTrials.gov |
The Influence of Hormone Replacement Therapy and Supervised Exercise Training on Body Composition, Cardiovascular Risk and Insulin Sensitivity in Postmenopausal Women | University Hospital, Ghent | N/A (non-drug) | Recruiting | 2023-05-12 | 2027-12-31 (est.) | 390 | Belgium | Female | 2025-11-18 |
| 2024-512071-12-00 EU CTIS |
The role of online sleep intervention and hormone therapy on sleep, climacteric symptoms and mood in the perimenopause | Amsterdam UMC Stichting | Phase 4 | Ongoing, recruiting | 2025-10-29 | — | — | Netherlands | Female | 2025-10-22 |
| NCT07210229 ClinicalTrials.gov |
The Effectiveness of a Proprietary Ashwagandha Extract on Menopausal Symptoms: A Three-Arm Randomized, Double-Blinded, Placebo Controlled Clinical Trial | Nutraceuticals Research Institute | N/A (non-drug) | Not yet recruiting | 2025-10-01 (est.) | 2026-02-28 (est.) | 90 | United States | Female | 2025-10-07 |
| NCT07022925 ClinicalTrials.gov |
A Trial to Investigate the Accuracy of a Wearable Device in Collecting Data Related to Perimenopausal Symptoms in Women | IdentifyHer Limited | Observational | Recruiting | 2025-07-04 | 2025-10 (est.) | 110 | Canada | Female | 2025-09-18 |
| NCT07160127 ClinicalTrials.gov |
A Clinical Study of Chinese Herbal Formula TJAOA103 in Treating Genitourinary Syndrome of Menopause | Tongji Hospital | Early Phase 1 | Not yet recruiting | 2025-09-15 (est.) | 2027-06-15 (est.) | 113 | China | Female | 2025-09-17 |
| NCT06787066 ClinicalTrials.gov |
Sympathetic Vascular Transduction Across the Menopause Transition: Contributing Mechanisms | University of Missouri-Columbia | Early Phase 1 | Recruiting | 2025-07-10 | 2026-12 (est.) | 75 | United States | Female | 2025-09-15 |
| NCT07034976 ClinicalTrials.gov |
Efficacy of Non-ablative Radiofrequency Combined With Pelvic Floor Muscle Training for Genitourinary Syndrome of Menopause in Breast Cancer Survivors (RF-SGM) | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | N/A (non-drug) | Recruiting | 2025-09-01 | 2026-12-31 (est.) | 50 | Spain | Female | 2025-09-15 |
| NCT07151482 ClinicalTrials.gov |
Impact of Oral Supplementation With Bioactive Collagen Peptides and Other Functional Ingredients | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Observational | Not yet recruiting | 2025-09-01 (est.) | 2027-09-01 (est.) | 43 | — | Female | 2025-09-03 |
| NCT07149285 ClinicalTrials.gov |
Effect of Mandala Practice on Menopausal Symptoms and Quality of Life | Emine Karacan | N/A (non-drug) | Not yet recruiting | 2025-09 (est.) | 2025-09 (est.) | 78 | Turkey (Türkiye) | Female | 2025-08-29 |
| NCT07146321 ClinicalTrials.gov |
A Study to Investigate the Effect of a Multivitamin, Multi-nutrient Supplement on Mental and Emotional Wellbeing | Biologica Inc | N/A (non-drug) | Not yet recruiting | 2025-09-01 (est.) | 2026-03-09 (est.) | 80 | United States | Female | 2025-08-28 |
| NCT07141953 ClinicalTrials.gov |
Yoga in Women With Surgical Menopause After Gynecological Cancer | Dokuz Eylul University | N/A (non-drug) | Not yet recruiting | 2025-09-01 (est.) | 2026-01-01 (est.) | 46 | Turkey (Türkiye) | Female | 2025-08-26 |
| NCT06306404 ClinicalTrials.gov |
Sleeping Through Menopause | VU University of Amsterdam | Phase 4 | Not yet recruiting | 2025-10-01 (est.) | 2029-10-01 (est.) | 222 | — | Female | 2025-08-24 |
| NCT07136220 ClinicalTrials.gov |
A Pilot Study to Evaluate Equol and Its Effects on Menopausal Symptoms Experienced by Women in Singapore | Ang Seng Bin | Observational | Recruiting | 2025-07-02 | 2025-12 (est.) | 300 | Singapore | Female | 2025-08-22 |
| NCT07120542 ClinicalTrials.gov |
Menopausal Impact on Skin Aging Among Egyptian Women | Sohag University | Observational | Not yet recruiting | 2025-11-01 (est.) | 2026-11 (est.) | 500 | — | Female | 2025-08-13 |
| NCT07100639 ClinicalTrials.gov |
Singapore Population Research on Integrated exposoMe & Early Menopause | Institute for Human Development and Potential (IHDP), Singapore | Observational | Not yet recruiting | 2025-08-06 (est.) | 2028-03-31 (est.) | 400 | — | Female | 2025-08-03 |
| NCT06732843 ClinicalTrials.gov |
Does Recombinant FSH (rFSH, i.g. Gonal F®) as Compared to Human Menopausal Gonadotrophin (hMG) Affect Telomere Length of Cumulus Cells During Antral Follicle Growth and Impact Blastocyst Status? | ART Fertility Clinics LLC | Observational | Recruiting | 2025-07-23 | 2026-12-31 (est.) | 10 | United Arab Emirates | Female | 2025-07-25 |
| NCT07034885 ClinicalTrials.gov |
Effects of Mindfulness-Based Self-Efficacy Development Program on Postmenopausal Women | Nurcan Gökgöz | N/A (non-drug) | Not yet recruiting | 2025-09-15 (est.) | 2026-01 (est.) | 70 | Turkey (Türkiye) | Female | 2025-07-22 |
| NCT07070635 ClinicalTrials.gov |
Abertay Tea for Cardiovascular Health During Menopause | Abertay University | N/A (non-drug) | Recruiting | 2025-06-16 | 2025-10 (est.) | 44 | United Kingdom | Female | 2025-07-17 |
| NCT07033013 ClinicalTrials.gov |
A Randomized, Double Blind, Placebo Controlled, Clinical Study to Examine the Benefits of an Oral Product in Panelists With Menopausal Symptoms Including Vasomotor Symptoms (VMS). | Olly, PBC | N/A (non-drug) | Recruiting | 2025-07-07 | 2025-07-25 (est.) | 40 | United States | Female | 2025-07-16 |
| NCT07042737 ClinicalTrials.gov |
The Effect of Animation-Based Education on Menopausal Women's Attitudes, Behaviors, and Screening Test Participation Regarding Breast Cancer | Inonu University | N/A (non-drug) | Not yet recruiting | 2025-06-20 (est.) | 2025-07-31 (est.) | 136 | Turkey (Türkiye) | Female | 2025-06-29 |
| NCT07021664 ClinicalTrials.gov |
Health, Imaging, and Cognition Across the Menopausal Transition | Université de Sherbrooke | Observational | Not yet recruiting | 2025-07-01 (est.) | 2026-03-01 (est.) | 45 | Canada | Female | 2025-06-15 |
| 2025-520741-68-00 EU CTIS |
Genitourinary Syndrome and Female Sexual Dysfunction: Effect of topical glyceryl trinitrate on female genital function in the peri- and postmenopause – a Pilot Study | Medical University Of Vienna | Phase 1 | Authorised, recruitment pending | — | — | — | Austria | Female | 2025-06-02 |
| NCT06644573 ClinicalTrials.gov |
Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia | Nyree Penn | Phase 1 | Not yet recruiting | 2025-11-01 (est.) | 2026-05-01 (est.) | 100 | United States | All | 2025-05-28 |
| NCT06852755 ClinicalTrials.gov |
Development of Biomarkers for Monitoring Menopause in Women | Fu Jen Catholic University Hospital | Observational | Recruiting | 2024-07-30 | 2026-02 (est.) | 100 | Taiwan | Female | 2025-05-25 |
| NCT06710002 ClinicalTrials.gov |
Effectiveness of a Telerehabilitation Program for Improving Sexual Function and Reducing Pain in Menopausal Women | Instituto Médico Tecnológico SL | N/A (non-drug) | Recruiting | 2025-05-05 | 2026-03 (est.) | 90 | Spain | Female | 2025-05-23 |
| 2024-520234-30-00 EU CTIS |
A randomized, double-blind, placebo-controlled, multicenter study evaluating the effect of a 12-week DHEA combination of 20 mg and 2 mg prolonged-release melatonin on sleep quality and mood in postmenopausal women. | The Pharmaceutical Company LEK-AM Sp. Zoo., Przedsiebiorstwo Farmaceutyczne Lek-Am Sp. z o.o. | Phase 3 | Ongoing, recruiting | 2024-11-30 | — | — | Poland | Female | 2025-05-13 |
| NCT05483634 ClinicalTrials.gov |
Compare Vaginal Estrogen and Platelet-rich Plasma Over Women With Genitourinary Syndrome of Menopause | Mackay Memorial Hospital | Observational | Not yet recruiting | 2025-12-01 (est.) | 2026-12-31 (est.) | 40 | Taiwan | Female | 2025-05-09 |
| NCT06959745 ClinicalTrials.gov |
Magnesium-L-Threonate Improves Menopausal Symptoms | Guangdong Provincial People's Hospital | N/A (non-drug) | Not yet recruiting | 2025-05-15 (est.) | 2025-09-30 (est.) | 50 | China | Female | 2025-05-07 |
| NCT06950463 ClinicalTrials.gov |
EFFECT OF CIRCUIT TRAINING ON BONE MINERAL DENSITY IN POST MENOPAUSAL PERIOD | Cairo University | N/A (non-drug) | Recruiting | 2025-01-01 | 2025-06-01 (est.) | 44 | Egypt | Female | 2025-04-30 |
| NCT06721936 ClinicalTrials.gov |
Genitourinary Syndrome of Menopause in Breast Cancer | University of Alcala | N/A (non-drug) | Recruiting | 2024-11-29 | 2027-12-31 (est.) | 182 | Spain | Female | 2025-04-27 |
| NCT06939868 ClinicalTrials.gov |
Effect of a Cepham Supplement on Hot Flashes and Menopausal Symptoms in Postmenopausal Women | Jacksonville University | N/A (non-drug) | Not yet recruiting | 2025-05-01 (est.) | 2025-08-30 (est.) | 44 | United States | Female | 2025-04-23 |
| NCT06899243 ClinicalTrials.gov |
Efficacy of CL22205 on Bone Mineral Density and Menopausal Symptoms | Eetho Brands, Inc | N/A (non-drug) | Not yet recruiting | 2025-03-25 (est.) | 2026-05-10 (est.) | 80 | — | Female | 2025-03-27 |
| NCT04305808 ClinicalTrials.gov |
Characterization of Vaginal, Urinary and Fecal Microbiomes in Women with Recurrent Urinary Tract Infections | Hadassah Medical Organization | Observational | Recruiting | 2021-08-01 | 2025-12-30 (est.) | 40 | Israel | Female | 2025-03-19 |
| NCT06222073 ClinicalTrials.gov |
Getting Under the Skin of the Menopausal Hot Flush | Liverpool John Moores University | Observational | Recruiting | 2023-01-01 | 2025-10-31 (est.) | 36 | United Kingdom | Female | 2025-03-18 |
| NCT06879938 ClinicalTrials.gov |
Concomitant Treatment with Topical Hyaluronic Acid and High Concentration Oxygen Therapy (Vaginal Natural Oxygenation Device - VNOD) in the Improvement of Symptoms Related to Genitourinary Syndrome of Menopause in Women with Natural and Oncological Postmenopause: Open-Label, Single-Center, Randomize | Fondazione IRCCS Policlinico San Matteo di Pavia | N/A (non-drug) | Recruiting | 2023-10-16 | 2025-12 (est.) | 80 | Italy | Female | 2025-03-17 |
| NCT06874738 ClinicalTrials.gov |
A Real-world Clinical Study on the Treatment of Menopausal Syndrome With Liuwei Dihuang Pills | China Academy of Chinese Medical Sciences | Observational | Not yet recruiting | 2025-03-08 (est.) | 2026-12-30 (est.) | 1,000 | — | Female | 2025-03-13 |
| NCT06865066 ClinicalTrials.gov |
Internet-Delivered Cognitive Behaviour Therapy for Women with Perimenopausal Anxiety | Dr. Nazanin Alavi | N/A (non-drug) | Recruiting | 2024-11-11 | 2025-02-28 (est.) | 25 | Canada | Female | 2025-03-07 |
| NCT06864520 ClinicalTrials.gov |
Evaluation of the Beneficial Effects of a Product Containing Γ-aminobutyric Acid (GABA) on Climacteric Syndrome Disorders | Ospedale Policlinico San Martino | N/A (non-drug) | Recruiting | 2023-10-25 | 2025-11 (est.) | 112 | Italy | Female | 2025-03-07 |
| NCT06848829 ClinicalTrials.gov |
Difference of Tear Ferning Between Women with and Without Menopausal. | Chung Shan Medical University | N/A (non-drug) | Recruiting | 2024-10-01 | 2025-09-01 (est.) | 90 | Taiwan | Female | 2025-02-27 |
| NCT06831890 ClinicalTrials.gov |
Surrogating Physician-recorded SCORE2 Risk Calculator Inputs by Using Auxiliary Data | Insel Gruppe AG, University Hospital Bern | Observational | Recruiting | 2023-08-24 | 2025-03 (est.) | 250 | Switzerland | Female | 2025-02-18 |
| NCT06798584 ClinicalTrials.gov |
How Does Perimenopausal Menorrhagia Affect Women's Quality of Life and Cognitive Function? | Purdue University | N/A (non-drug) | Not yet recruiting | 2025-03-01 (est.) | 2025-12 (est.) | 240 | United States | Female | 2025-02-13 |
| NCT06808347 ClinicalTrials.gov |
Difference in Serum Estrogen Level Based on Methods of Vaginal Estrogen Application (fingertip Vs Applicator Use) in Post-menopausal Women | Walter Reed National Military Medical Center | Phase 4 | Not yet recruiting | 2025-02-01 (est.) | 2025-06-30 (est.) | 110 | — | Female | 2025-02-05 |
| NCT06806501 ClinicalTrials.gov |
Muscle Mass, Quality, and the Menopause: Sex-specific Strategies to Mitigate Sarcopenia in Ageing Populations | University of Nottingham | Observational | Recruiting | 2024-07-29 | 2026-03 (est.) | 18 | United Kingdom | Female | 2025-02-04 |
| NCT06106529 ClinicalTrials.gov |
REDucing Hot FLASHes in Women Using Endocrine Therapy. | Reinier de Graaf Groep | Phase 3 | Recruiting | 2024-10-03 | 2029-01-01 (est.) | 260 | Netherlands | Female | 2025-02-04 |
| NCT06030388 ClinicalTrials.gov |
Strength and Aerobic Training Against Hot Flushes in Postmenopausal Women | Linkoeping University | N/A (non-drug) | Recruiting | 2023-09-12 | 2027-06 (est.) | 90 | Sweden | Female | 2025-01-22 |
| NCT06704516 ClinicalTrials.gov |
COmmencing Menopausal HOrmone Replacement Therapy and the Effect on Metabolic-dysfunction Associated Steatotic Liver Disease: a Pilot Mechanistic Study | University of Oxford | Phase 1 | Recruiting | 2025-01 (est.) | 2025-08-05 (est.) | 10 | United Kingdom | Female | 2025-01-13 |
| NCT06768073 ClinicalTrials.gov |
Intravaginal Negative Pressure Medical Device for Treatment of Genitourinary Syndrome of Menopause (GSM) | AVeta Medical | N/A (non-drug) | Not yet recruiting | 2025-03-03 (est.) | 2025-11-03 (est.) | 60 | Georgia, United States | Female | 2025-01-10 |
| NCT06750263 ClinicalTrials.gov |
Effects of Balance Exercises With and Without Clamshell Exercises After Menopause | Riphah International University | N/A (non-drug) | Not yet recruiting | 2024-12-15 (est.) | 2025-04-15 (est.) | 80 | — | Female | 2024-12-27 |
| NCT06726746 ClinicalTrials.gov |
Efficacy of Fractional CO2 Laser Treatment in Post-Menopausal Women With Vaginal Atrophy | Cairo University | N/A (non-drug) | Recruiting | 2023-10-01 | 2025-03-01 (est.) | 20 | Egypt | Female | 2024-12-10 |
| NCT06007027 ClinicalTrials.gov |
Vaginal CO2 Laser Therapy for Genitourinary Syndrome in Breast Cancer Survivors | University of Aarhus | N/A (non-drug) | Recruiting | 2024-12-01 | 2026-01-30 (est.) | 60 | Denmark | Female | 2024-12-05 |
| NCT06716554 ClinicalTrials.gov |
Efficacy and Safety of Shatavari for Treatment of Menopausal Symptoms in Women: A Randomized, Double-blind, Three-arm, Parallel, Placebo-controlled Study | SF Research Institute, Inc. | N/A (non-drug) | Recruiting | 2024-10-26 | 2024-12-26 (est.) | 51 | United States | Female | 2024-12-04 |
| NCT04478305 ClinicalTrials.gov |
Affect of Duavive on Mood & Anxiety Symptoms | St. Joseph's Healthcare Hamilton | Phase 1 | Recruiting | 2024-07-03 | 2025-12 (est.) | 30 | Canada | Female | 2024-12-03 |
| NCT06710015 ClinicalTrials.gov |
Study on Fertility Parameters in Women With Germline Variants in BRCA1 and BRCA2 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Observational | Not yet recruiting | 2024-12-01 (est.) | 2025-12-01 (est.) | 128 | Italy | Female | 2024-11-29 |
| NCT06709664 ClinicalTrials.gov |
Perimenopause and Menopause in Women With Spinal Cord Injury | James Cooper | Observational | Not yet recruiting | 2025-01 (est.) | 2025-08 (est.) | 100 | — | Female | 2024-11-29 |
| NCT06611514 ClinicalTrials.gov |
Effect of Intravaginal Prasterone on Symptoms of Genitourinary Syndrome of Menopause (GSM) in Women in Menopause With Previous Breast Cancer | European Institute of Oncology | Phase 3 | Not yet recruiting | 2024-12-01 (est.) | 2027-01-01 (est.) | 95 | Italy | Female | 2024-11-19 |
| NCT06082817 ClinicalTrials.gov |
An Open-Label Study of 50 Mg Oral Testosterone Undecanoate (Kyztrex) in Menopausal Women with Low Testosterone and HSDD | San Diego Sexual Medicine | Phase 2 | Not yet recruiting | 2025-01-01 (est.) | 2025-12-31 (est.) | 30 | United States | Female | 2024-11-13 |
| NCT06659380 ClinicalTrials.gov |
Probiotic Efficacy in Postmenopausal Women with Bacterial Vaginosis | Hasanuddin University | N/A (non-drug) | Recruiting | 2024-06-26 | 2024-12-31 (est.) | 12 | Indonesia | Female | 2024-10-28 |
| NCT06634550 ClinicalTrials.gov |
Effect of Mulligan Technique Versus Core Stability Exercises on Low Back Pain in Post Menopausal Women | Cairo University | N/A (non-drug) | Not yet recruiting | 2024-10-15 (est.) | 2025-01-15 (est.) | 60 | Egypt | Female | 2024-10-10 |
| NCT06578715 ClinicalTrials.gov |
Emotional Freedom Technique (EFT) Applied to Postmenopausal Women on Sleep and Quality of Life | Ataturk University | N/A (non-drug) | Not yet recruiting | 2024-10-01 (est.) | 2024-10-01 (est.) | 80 | — | Female | 2024-10-02 |
| NCT06336564 ClinicalTrials.gov |
Microablative Radiofrequency in the Treatment of Urinary Symptoms Associated With Genitourinary Syndrome of Menopause | Centro de Atenção ao Assoalho Pélvico | N/A (non-drug) | Not yet recruiting | 2025-08 (est.) | 2026-08 (est.) | 40 | Brazil | Female | 2024-08-20 |
| NCT06530459 ClinicalTrials.gov |
The MUSE Study for Menopausal Arthralgia | National University Hospital, Singapore | Phase 2/3 | Recruiting | 2024-08-01 (est.) | 2027-04 (est.) | 100 | Singapore | Female | 2024-07-31 |
| NCT06487130 ClinicalTrials.gov |
Virtual perI-/Menopause Registry of AusTrALia | Bespoke Clinical Research | Observational | Recruiting | 2023-08-03 | 2073-08 (est.) | 10,000 | Australia | All | 2024-07-05 |
| NCT04196595 ClinicalTrials.gov |
Apple Women's Health Study | Apple Inc. | Observational | Recruiting | 2019-11-14 | 2029-11 (est.) | 500,000 | United States | All | 2024-07-03 |
| NCT06264882 ClinicalTrials.gov |
Cardiometabolic Consequences of the Loss of Ovarian Function | University of Colorado, Denver | Phase 4 | Recruiting | 2024-06-01 | 2028-05-31 (est.) | 100 | United States | Female | 2024-06-20 |
| NCT05280028 ClinicalTrials.gov |
HRT on Overactive Bladder Symptoms, Sexual Function, Depressive Symptoms, Autonomic Function, and Arterial Stiffness | Far Eastern Memorial Hospital | Observational | Recruiting | 2022-02-07 | 2026-12-31 (est.) | 100 | Taiwan | Female | 2024-06-17 |
| NCT05586724 ClinicalTrials.gov |
Micronized Progesterone Versus Norethisterone Acetate in Combination With Estrogen as Menopausal Hormone Therapy | Angelica Lindén Hirschberg | Phase 3 | Recruiting | 2022-03-15 | 2026-09 (est.) | 520 | Sweden | Female | 2024-06-04 |
| NCT06151028 ClinicalTrials.gov |
An Observational Study of Menopausal Symptom in Patients With Gynecological Malignancy After Oophorectomy | Anhui Provincial Hospital | Observational | Recruiting | 2023-12-01 | 2028-12-31 (est.) | 490 | China | Female | 2024-03-07 |
| NCT06261658 ClinicalTrials.gov |
Improving the Quality of Cryopreserved Ovarian Tissue Reimplantation Using Platelet-enriched Autologous Plasma | IRCCS Azienda Ospedaliero-Universitaria di Bologna | N/A (non-drug) | Recruiting | 2024-03-01 (est.) | 2024-12-29 (est.) | 45 | Italy | Female | 2024-02-15 |
| NCT04043520 ClinicalTrials.gov |
Bioenergetic Effects of Aging and Menopause (BEAM) | University of Colorado, Denver | Phase 4 | Recruiting | 2019-09-24 | 2024-08-31 (est.) | 57 | United States | Female | 2023-12-18 |
| NCT05985447 ClinicalTrials.gov |
Menopause Related Influences on Leukocyte Distribution, Monocyte Function and Platelet Reactivity | Heinrich-Heine University, Duesseldorf | Observational | Recruiting | 2022-03-07 | 2025-12 (est.) | 180 | Germany | All | 2023-08-14 |
| NCT05647876 ClinicalTrials.gov |
A Longitudinal Study to Identify Mechanisms of Menopause on Cardiovascular Disease Risk | University of Copenhagen | Observational | Recruiting | 2022-12-16 | 2040-12 (est.) | 200 | Denmark | Female | 2023-05-10 |
| NCT05613504 ClinicalTrials.gov |
Study of Acupuncture in the Treatment of Hot Flashes in Patients With Hormone Receptor-positive Breast Cancer. | Nanjing University of Traditional Chinese Medicine | N/A (non-drug) | Not yet recruiting | 2022-12-01 (est.) | 2027-12-01 (est.) | 90 | China | Female | 2022-11-16 |
| NCT05460819 ClinicalTrials.gov |
Acupuncture for Hot Flashes in Patients With Hormone Receptor-positive Breast Cancer. | Nanjing University of Traditional Chinese Medicine | N/A (non-drug) | Not yet recruiting | 2022-08-01 (est.) | 2027-07-31 (est.) | 90 | China | Female | 2022-07-20 |
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- US and EU registries merged and de-noised
- Plain-English one-line summary per change
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Coming next: women-representation scoring Preview · not live
Representation scoring isn't meaningful for menopause, because nearly all of these trials enrol only women. On mixed-sex trials (heart disease, oncology, neurology and so on), TrialsForHer will compare the share of women enrolled against the share of women living with the condition. That is the participation-to-prevalence ratio used in FDA and academic analyses. It will also flag trials that don't report results by sex. Scores will come only from registry-reported baseline data, with links to the source, and no scores are shown on this page.
Methodology
- US: ClinicalTrials.gov API v2, condition search
menopause OR perimenopause OR "vasomotor symptoms" OR "hot flashes" OR "hot flushes"(1,448 records in total). Listed here: recruiting or not yet recruiting (275), plus any record updated or first posting results in the last 90 days. - EU: CTIS public search API, full-text and medical-condition searches for the same terms (19 trials; CTIS covers EU trials submitted under the Clinical Trials Regulation since 2023). Listed here: authorised or ongoing and recruiting (9), plus any record updated in the last 90 days. Off-topic matches are removed with a keyword check on each record's conditions and title, and male-only trials are excluded (729 removed this run).
- "Updated" means the registry's last-update date. It can be any change, from a new site to a status change.
- Phases are grouped across both registries (for example, CTIS "Therapeutic exploratory (Phase II)" → Phase 2). "N/A" means a device, procedure or behavioural study.
- Site share counts open trials with at least one site in the US or the EU-27. A multinational trial can count in both.
- Fields are shown as the registry records them, and "(est.)" marks the sponsor's estimated dates. A trial registered in both systems may appear twice.
- Data pulled 21 Oct 2026, 10:06 UTC and regenerated automatically.
Sources
- ClinicalTrials.gov API v2, U.S. National Library of Medicine
- EU Clinical Trials Information System (CTIS), European Medicines Agency
Disclaimer
Business research data, not medical advice. TrialsForHer summarises public registry records for professional and research use. It isn't medical advice, doesn't recommend or endorse any trial or treatment, and isn't a way to enrol in a study. Registry entries can be incomplete or out of date, so always check the official record. If you're a patient or carer, talk to your clinician or contact the study team listed on the registry.